Product Information
Name:AT-9283
Synonyms:
- 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea
- N-Cyclopropyl-N'-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-urea
Brand:TRC
Description:
Applications AT-9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor. AT-9283 has shown to inhibit growth and survival of multiple solid tumor cell lines and is efficacious in mouse xenograft models. It is a COVID19-related research product.
References Curry, J., et. al.: Cell Cycle, 8, 1921 (2009)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:381.43
Formula:C19H23N7O2
Color/Form:Neat
InChI:InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13H,2-3,5-8,11H2,(H,20,25)(H,22,23)(H2,21,24,27)
InChI key:InChIKey=LOLPPWBBNUVNQZ-UHFFFAOYSA-N
SMILES:O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)NC1CC1
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