CAS 90-49-3

Pheneturide

Description:

Pheneturide, with the CAS number 90-49-3, is a chemical compound that belongs to the class of organic compounds known as amides. It is characterized by its structure, which includes a phenyl group attached to an ethyl group and an amide functional group. This compound is typically a white to off-white crystalline solid and is known for its use in medicinal chemistry, particularly as an anticonvulsant agent. Pheneturide exhibits moderate solubility in water and is more soluble in organic solvents, which is common for many amides. Its pharmacological properties include the ability to modulate neuronal excitability, making it relevant in the treatment of epilepsy. Additionally, like many amides, it may undergo hydrolysis under certain conditions, leading to the formation of the corresponding carboxylic acid and amine. Safety data indicates that, while it has therapeutic applications, it should be handled with care due to potential side effects and toxicity associated with its use.

Formula: C₁₁H₁₄N₂O₂

InChI: InChI=1S/C11H14N2O2/c1-2-9(10(14)13-11(12)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H3,12,13,14,15)

InChI key: InChIKey=AJOQSQHYDOFIOX-UHFFFAOYSA-N

SMILES: C(C(NC(N)=O)=O)(CC)C1=CC=CC=C1

Synonyms:

• (2-Phenylbutanoyl)urea
• (2-Phenylbutyryl)Urea
• 1-[(Ethyl)phenylacetyl]urea
• 2-Phenylbutyrylurea
• Benuride
• Benzeneacetamide, N-(aminocarbonyl)-α-ethyl-
• Beta�methoxynaph-talene
• Ethylphenacemide
• Lircapyl
• M 551
• N-(Aminocarbonyl)-α-ethylbenzeneacetamide
• N-(α-Phenylbutyryl)urea
• N-carbamoyl-2-phenylbutanamide
• Phenuride
• Phenylethylacetylurea
• Urea, (2-phenylbutyryl)-
• dl-Pheneturide

Pheneturide

CAS: 90-49-3

Pheneturide

Formula: C₁₁H₁₄N₂O₂

Purity: ≥98%

Molecular weight: 206.24

Ref: 54-BUP06669

Pheneturide

CAS: 90-49-3

Pheneturide

Formula: C₁₁H₁₄N₂O₂

Purity: 99%

Molecular weight: 206.24

Ref: 54-OR1024015

Phenylethylacetylurea (2-Phenylbutyrylurea)

CAS: 90-49-3

Color and Shape: Neat

Ref: 61-FOR0265.01

Phenylethylacetylurea (2-Phenylbutyrylurea)

Controlled Product

CAS: 90-49-3

Formula: C₁₁H₁₄N₂O₂

Color and Shape: Neat

Molecular weight: 206.24

Ref: 86-MM0265.01

2-Phenylbutyrylurea

CAS: 90-49-3

Formula: C₁₁H₁₄N₂O₂

Molecular weight: 206.25

Ref: 4Z-U-0613

Pheneturide

CAS: 90-49-3

Pheneturide (Benuride) is the ureide class, used to treat epilepsy, and is an anticonvulsant.

Formula: C₁₁H₁₄N₂O₂

Purity: 99.72%

Color and Shape: White Solid

Molecular weight: 206.24

Ref: TM-T8594

2-Phenylbutyrylurea

CAS: 90-49-3

Applications 2-Phenylbutyrylurea is used in the synthesis and discovery of novel trypanosomicidal drug-like compounds which is useful in the treatment of diseases. A degradation product of Phenobarbitol (P316760).
References Castillo-Garit, J. et al.; Eur. J. Med. Chem., 46, 3324 (2011);

Formula: C₁₁H₁₄N₂O₂

Color and Shape: Neat

Molecular weight: 206.24

Ref: TR-P320945

Pheneturide

CAS: 90-49-3

2-Phenylbutyrylurea

Formula: C₁₁H₁₄N₂O₂

Purity: 99%

Molecular weight: 206.24

Ref: IN-DG78160

Pheneturide

CAS: 90-49-3

Purity: 97%

Color and Shape: Solid

Molecular weight: 206.2449951

Ref: 10-F601397

(2-Phenylbutanoyl)urea

CAS: 90-49-3

2-Phenylbutanoyl)urea is an enzyme inducer that belongs to the group of acidic compounds. It has been shown to be a potent inducer of drug metabolism enzymes, such as cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases. 2-Phenylbutanoyl)urea has also been shown to have a significant effect on the pharmacokinetics of drugs that are substrates for these enzymes. This compound is insoluble in water and soluble in organic solvents, like acetone. 2-Phenylbutanoyl)urea is soluble in organic solvents, like acetone, and insoluble in water. 2-Phenylbutanoyl)urea is used as a model system for studying enzyme induction by acidic compounds.

Formula: C₁₁H₁₄N₂O₂

Purity: Min. 95%

Molecular weight: 206.24 g/mol

Ref: 3D-AAA09049

(2-phenylbutanoyl)urea

CAS: 90-49-3

Formula: C₁₁H₁₄N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 206.2411

Ref: IN-DA00GR9L