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CAS 9001-84-7

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Phospholipase A2

Description:
Phospholipase A2 (PLA2) is an enzyme that plays a crucial role in the hydrolysis of phospholipids, specifically targeting the sn-2 acyl bond to release free fatty acids and lysophospholipids. This enzyme is widely distributed in various biological systems, including animal tissues, plants, and microorganisms. PLA2 is characterized by its ability to catalyze the breakdown of phospholipids, which are essential components of cell membranes, thus influencing membrane dynamics and signaling pathways. The enzyme is often involved in inflammatory responses and is a key player in the metabolism of arachidonic acid, a precursor for various bioactive lipids. PLA2 exhibits diverse isoforms, each with distinct properties and functions, and can be classified into several groups based on their structure and source. The enzyme's activity can be influenced by factors such as pH, temperature, and the presence of specific cofactors or inhibitors. Due to its biological significance, PLA2 is of interest in pharmacology and biotechnology, particularly in the development of therapeutic agents targeting inflammatory diseases.
Formula:Unspecified
InChI:InChI=1S/H3NO/c1-2/h2H,1H2
InChI key:AVXURJPOCDRRFD-UHFFFAOYSA-N
SMILES:NO
Synonyms:
  • Acanthoxin A1
  • Agelotoxin
  • Ammodytoxin C
  • Arachidonate phospholipase A<sub>2</sub>
  • Arachidonate-selective phospholipase A<sub>2</sub>
  • Arachidonate-specific phospholipase A2
  • Arachidonic acid-selective phospholipase A<sub>2</sub>
  • Arachidonic acid-specific phospholipase A2
  • Arachidonoyl-selective phospholipase A<sub>2</sub>
  • Cakezyme
  • See more synonyms
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