CAS 9004-54-0

Dextran

Description:

Dextran is a complex branched polysaccharide composed of glucose units linked primarily by α(1→6) glycosidic bonds, with occasional α(1→3) linkages. It is produced by certain bacteria, such as Leuconostoc mesenteroides, and is commonly used in various applications due to its biocompatibility and non-toxicity. Dextran is soluble in water, forming a viscous solution, and exhibits a high molecular weight, which can vary depending on the source and method of production. Its properties include being a stabilizer, thickening agent, and a medium for drug delivery in pharmaceuticals. Additionally, dextran is utilized in the food industry as a food additive and in medical applications, such as in blood volume expanders and as a component in diagnostic tests. Its ability to form gels and its low immunogenicity make it valuable in biotechnology and research. Overall, dextran's versatility and safety profile contribute to its widespread use across multiple fields.

Formula: Unspecified

Synonyms:

• Cdc-H
• Dextran11
• Dextran2
• Dextran5
• Dextranen
• DextrangradeA,B,C
• Dextrano
• Dextrans
• Dextraven
• Eudextran
• Ex-pandex
• Expandex
• Gentran
• Gentran3
• Hemodex
• Hyscon
• Hyskon
• Infucoll
• Intrader
• Intradex
• LMD
• LVD
• Lmwd
• Macrodex
• Macrose
• Mucrose
• Onkotin
• Plasmafusin
• Plasmodex
• Plavolex
• Polyglucin
• Polyglusol
• Promit
• R-gel
• Rheodextran
• Rheoisodex
• Rheomacrodex
• Rheopolyglucin
• Rheopolyglucine
• Rheorondex
• Rheotran
• Rondex
• Ultradex
• α-Dextran
• Dextran 70
• Dextran 40
• Glucose polymer
• Dextran 45

Dextran (Technical Grade~ 20K)

CAS: 9004-54-0

Applications Dextran is a polysaccharide composed of glucose molecules used as an antithrombotic to reduce blood viscosity and as a volume expander in anemia. Studies show that it inhibits the mannose receptor-mediated clearance of tissue-type plasminogen activator (t-PA).
References MacNeil, B.D. et al.: Fund. Clin. Cardiol., 52, 473 (2005); Noorman, F. et al.: Thromb. Haemost., 80, 210 (1998); Fushbane, S. et al.: Am. J. Kidney Dis., 28, 529 (1996);

Formula: H₂(C₆H₉O₅)n(C₇H₁₂O₅)mOH

Color and Shape: White To Off-White

Ref: TR-D299115

Dextran (Technical Grade~ 500K)

CAS: 9004-54-0

Applications Dextran is a polysaccharide composed of glucose molecules used as an antithrombotic to reduce blood viscosity and as a volume expander in anemia. Studies show that it inhibits the mannose receptor-mediated clearance of tissue-type plasminogen activator (t-PA).
References MacNeil, B.D. et al.: Fund. Clin. Cardiol., 52, 473 (2005); Noorman, F. et al.: Thromb. Haemost., 80, 210 (1998); Fushbane, S. et al.: Am. J. Kidney Dis., 28, 529 (1996);

Formula: H₂(C₆H₉O₅)n(C₇H₁₂O₅)mOH

Color and Shape: White To Off-White

Ref: TR-D299140

Dextran 3 - MW 2500 - 4000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose. The main use for native dextran is as a blood plasma extender in blood transfusions. A complex of iron with dextran, known as iron dextran, is used as a source of iron to baby piglets which are often anaemic at birth.

Color and Shape: White Off-White Powder

Ref: 3D-YD00049

Dextran 70 - MW 64,000 to 76,000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications.  A complex of Iiron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Color and Shape: White Off-White Powder

Ref: 3D-YD30645

Dextran 2000 - MW: 1,500,000 to 3,500,000

CAS: 9004-54-0

Dextran 2000 is a high molecular weight biocompatible polymer with transport properties. It is used in a variety of medical applications, such as red blood cell transfusions and the prevention of post-surgical adhesions. Dextran 2000 has been shown to be a safe and effective means of preventing hemolysis during red blood cell transfusion. This agent binds to amine groups on the surface of erythrocytes, which prevents complement activation and subsequent lysis. Additionally, dextran 2000 has been shown to exhibit low cytotoxicity against neuronal cells in vitro.

Purity: Min. 95%

Color and Shape: White Off-White Powder

Ref: 3D-OD156913

Dextran 6, MW 5,500 to 7,500

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Color and Shape: White Powder

Ref: 3D-YD35507

Dextran 60, MW: 54,000 to 66,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Formula: (C₆H₁₀O₅)n

Color and Shape: White Powder

Ref: 3D-OD156910

Dextran 750 - MW: 500,000 to 1,000,000

CAS: 9004-54-0

Dextran is a polysaccharide that is used as an antimicrobial agent and as a volume expander in the treatment of bowel disease, myocardial infarct, and other diseases. Dextran sulfate is a linear polymer with a molecular weight of 500,000 to 1,000,000. It has minimal toxicity and does not interfere with iron homeostasis or cause fluid overload. Dextran sulfate can be used for the treatment of bowel disease because it has been shown to have anti-inflammatory effects in experimental models. The mechanism by which dextran sulfate inhibits inflammation is unknown, but may involve its ability to bind to macrophages and neutrophils in the gut wall. Dextran sulfate also binds to bacteria and prevents their growth. This binding may prevent bacterial penetration into epithelial cells or block bacterial attachment to cell surfaces. The efficacy of dextran sulfate against pathogenic mechanisms such as inflammation has been demonstrated in experimental models.

Purity: Min. 95%

Color and Shape: White Powder

Ref: 3D-OD156906

Dextran 10 - MW 9,000 to 11,000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cutoff molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Color and Shape: White Powder

Ref: 3D-YD32417

Dextran 250 - MW: 225,000 to 275,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Color and Shape: Powder

Ref: 3D-OD156911

Dextran 40 - MW 35,000 to 45,000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cutoff molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Purity: Min. 95%

Color and Shape: White Powder

Ref: 3D-YD01481

Dextran 500 - MW 450,000 to 550,000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications.  A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Color and Shape: White Powder

Ref: 3D-YD34755

Dextran 5 - MW 4,000 to 6,000

CAS: 9004-54-0

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications. A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Color and Shape: White Powder

Ref: 3D-YD44759

Dextran T70 MW 70,000

CAS: 9004-54-0

Purity: Pharmaceutical grade,Mw64000-76000

Color and Shape: Solid

Molecular weight: 504.17

Ref: 10-F996432

Dextran, MW 40000

CAS: 9004-54-0

Purity: Pharmaceutical grade,Mw40000

Molecular weight: 504.17

Ref: 10-F996886

Dextran (~40K)

CAS: 9004-54-0

Formula: H₂(C₆H₉O₅)n(C₇H₁₂O₅)mOH

Color and Shape: White To Off-White

Ref: TR-D299270

Dextran 150 - MW: 135,000 to 165,000

CAS: 9004-54-0

Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions

Color and Shape: Powder

Ref: 3D-OD156908

Dextran ex. Leuconostoc Sp. - Tech 250 (225-275)

CAS: 9004-54-0

Formula: (C₆H₁₀O₅)n

Color and Shape: White to off-white, Powder, Clear, Colourless

Molecular weight: 250000

Ref: SR-62753

Dextran ex. Leuconostoc Sp. - Tech 40 (35-45)

CAS: 9004-54-0

Formula: (C₆H₁₀O₅)n

Color and Shape: White, Powder

Molecular weight: 35000 - 45000

Ref: SR-41570

Dextran ex. Leuconostoc Sp. - Tech 70 (65-75)

CAS: 9004-54-0

Formula: (C₆H₁₀O₅)n

Color and Shape: White to off white, Powder, Clear, Colourless

Ref: SR-12891