CAS 90098-04-7

Rebamipide

Description:

Rebamipide is a synthetic compound primarily used in the treatment of gastric mucosal injuries and ulcers. It is classified as a gastroprotective agent and is known for its ability to enhance mucosal defense mechanisms. The chemical structure of Rebamipide includes a 2-aminobenzothiazole moiety, which contributes to its pharmacological properties. It exhibits anti-inflammatory effects and promotes the synthesis of prostaglandins, which are crucial for maintaining gastric mucosal integrity. Additionally, Rebamipide has antioxidant properties, helping to neutralize free radicals that can damage gastric tissues. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its therapeutic effects are attributed to its ability to stimulate the production of mucus and bicarbonate, thereby protecting the gastric lining from harmful substances and promoting healing. Overall, Rebamipide is recognized for its role in enhancing gastric mucosal defense and is utilized in various gastrointestinal disorders.

Formula: C₁₉H₁₅ClN₂O₄

InChI: InChI=1/C19H15ClN2O4/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26)/t16-/m1/s1

InChI key: InChIKey=ALLWOAVDORUJLA-UHFFFAOYSA-N

SMILES: C(C(NC(=O)C1=CC=C(Cl)C=C1)C(O)=O)C=2C=3C(NC(=O)C2)=CC=CC3

Synonyms:

• (+-)-1,2-Dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoic acid
• +-)-2-(4-Chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
• 2-[(4-Chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (R)-
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (S)-
• 4-Quinolinepropanoic acid, α-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-
• Mucosta
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)-D-alanine
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine
• Opc 12759
• Proamipide
• Rebator
• α-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
• Rebamipide
• (+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-(9CI)
• REBAPIMIDE
• Rebamipid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoicaci
• (+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoic acid
• 2-(4-CHLOROBENZAMIDO)-3-(2-OXO-1,2-DIHYDROQUINOLIN-4-YL)PROPANOIC ACID
• RebamipideRebamipide
• 1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoicaci(
• opc12759
• REBAMIPIDE,99.5%
• OPC-12759, Mucosta, α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid

2-​(4-​Chloro-​benzoylamino)​-​3-​(2-​hydroxy-​quinolin-​4-​yl)​-​propionic acid

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.7864

Ref: IN-DA00IMK8

Rebamipide

CAS: 90098-04-7

Rebamipide (OPC12759) is a drug enhancing gastric defense by stimulating COX2, prostaglandins, and mucus, while reducing TNF alpha and free radicals.

Formula: C₁₉H₁₅ClN₂O₄

Purity: 99.48% - 99.61%

Color and Shape: White Solid

Molecular weight: 370.79

Ref: TM-T1562

Rebamipide

CAS: 90098-04-7

Rebamipide

Formula: C₁₉H₁₅ClN₂O₄

Purity: ≥98%

Molecular weight: 370.79

Ref: 54-BUP18316

Rebamipide hydrate

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄·xH₂O

Purity: ≥ 99.0% (dried basis)

Color and Shape: White crystalline powder

Molecular weight: 370.79 (anhydrous)

Ref: 7W-GP6330

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

CAS: 90098-04-7

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

Formula: C₁₉H₁₅ClN₂O₄

Purity: 98%

Molecular weight: 370.79

Ref: 54-OR1009762

Rebamipide

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 370.79

Ref: 4Z-R-085005

Rebamipide

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 370.79

Ref: 3B-R0085

Rebamipide

CAS: 90098-04-7

2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid

Formula: C₁₉H₁₅ClN₂O₄

Purity: 98%

Molecular weight: 370.79

Ref: IN-DG287434

Rebamipide

Controlled Product

CAS: 90098-04-7

Applications Shows antiulcer activity in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Uchida, M., et al.: Chem. Pharm. Bull., 33, 3775 (1985), Yamasaki, K., et al.: Eur. J. Pharmacol., 142, 23 (1987),

Formula: C₁₉H₁₅ClN₂O₄

Color and Shape: Neat

Molecular weight: 370.79

Ref: TR-R139000

Rebamipide - Bio-X ™

CAS: 90098-04-7

Rebamipide is a gastroprotective agent that is used to treat various gastrointestinal disorders such as gastric ulcers and GERD. This drug’s mechanism of action is not fully understood however, it is thought to exert its effects by promoting the secretion of protective mucus in the stomach and intestine, which helps to create a barrier against stomach acid and other irritants. Additionally, it has antioxidant and anti-inflammatory properties that can help reduce tissue damage.

Formula: C₁₉H₁₅ClN₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 370.79 g/mol

Ref: 3D-BC164330

Rebamipide

CAS: 90098-04-7

COX-2 positive regulator; gastroprotective; anti-inflammatory; anti-ulcer agent

Formula: C₁₉H₁₅ClN₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 370.79 g/mol

Ref: 3D-FC15908

2-(4-CHLOROBENZOYLAMINO)-3-(1,2-DIHYDRO-2-OXO-4-QUINOLYL)PROPIONIC ACID

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.79

Ref: 10-F300998

Rebamipide

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Molecular weight: 370.8

Ref: ST-EA-CP-R45000