CAS 908-54-3

Berenil

Description:

Berenil, with the CAS number 908-54-3, is a chemical compound primarily used as an antiprotozoal agent, particularly in veterinary medicine for the treatment of trypanosomiasis, commonly known as sleeping sickness in humans and Nagana in animals. It is classified as a diamidine derivative and exhibits a broad spectrum of activity against various protozoan parasites. Berenil is known for its ability to interfere with the nucleic acid metabolism of the parasites, leading to their death. The compound is typically administered via injection and is characterized by its relatively low solubility in water, which can influence its formulation and delivery. In terms of safety, Berenil has been associated with certain side effects, including potential toxicity, which necessitates careful dosing and monitoring during treatment. Its use is regulated in many countries, and it is essential to follow veterinary guidelines when administering this medication. Overall, Berenil plays a significant role in managing parasitic infections in livestock and has implications for public health in regions affected by trypanosomiasis.

Formula: C₁₄H₁₅N₇·2C₄H₇NO₃

InChI: InChI=1S/C14H15N7.C4H7NO3/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18;1-3(6)5-2-4(7)8/h1-8H,(H3,15,16)(H3,17,18)(H,19,20);2H2,1H3,(H,5,6)(H,7,8)

InChI key: InChIKey=XJLITJHUQRBWPN-UHFFFAOYSA-N

SMILES: C(NC(C)=O)C(O)=O.C(=N)(N)C1=CC=C(N=NNC2=CC=C(C(=N)N)C=C2)C=C1

Synonyms:

• 1,3-Bis(p-amidinophenyl)triazene bis(N-acetylglycinate)
• 1,3-Bis[4-guanylphenyl]triazene diaceturate
• 4,4'-(Diamino)Dibenzamidediaceturate
• 4,4′-(Diazoamino)dibenzamidine diaceturate
• 4,4′-Diamidinodiazoaminobenzene diaceturate
• Azidin
• Azidine
• Benzamidine, 4,4′-(diazoamino)di-, compd. with N-acetylglycine (1:2)
• Benzamidine, 4,4′-diazoaminodi-, diaceturate
• Benzenecarboximidamide, 4,4′-(1-triazene-1,3-diyl)bis-, compd. with N-acetylglycine (1:2)
• Berenil
• Beronal
• Di-(4-amidinophenyl)-triazine-(N-1,3)-diaceturate
• Diaminazene aceturate
• Diiminazene Aceturate
• Diminasan
• Diminazene diaceturate
• Diminazine aceturate
• Diminazine diaceturate
• Fatrybanil
• Ganasag
• Ganaseg
• Glycine, N-acetyl-, compd. with 4,4′-(1-triazene-1,3-diyl)bis[benzenecarboximidamide] (2:1)
• Glycine, N-acetyl-, compd. with 4,4′-(azoamino)dibenzamidine
• Glycine, N-acetyl-, compd. with 4,4′-(diazoamino)dibenzamidine (2:1)
• N-acetylglycine - 4,4'-(1E)-triaz-1-ene-1,3-diyldibenzenecarboximidamide (1:1)
• N-acetylglycine - 4-[(1E)-3-(4-carbamimidoylphenyl)triaz-1-en-1-yl]benzenecarboximidamide (2:1)
• Neozidin-M
• Tricip Plus
• Veriben

4,4'-(Triaz-1-Ene-1,3-Diyl)Dibenzimidamide Bis(2-Acetamidoacetate)

CAS: 908-54-3

4,4'-(Triaz-1-Ene-1,3-Diyl)Dibenzimidamide Bis(2-Acetamidoacetate)

Formula: C₂₂H₂₉N₉O₆

Purity: 98%

Molecular weight: 515.52

Ref: 54-OR1030499

Diminazene aceturate

CAS: 908-54-3

4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide bis(2-acetamidoacetate)

Formula: C₂₂H₂₉N₉O₆

Purity: 98%

Molecular weight: 515.52

Ref: IN-DG125646

Diminazene Aceturate

CAS: 908-54-3

Diminazene is a trypanocidal agent.

Formula: C₂₂H₂₉N₉O₆

Purity: 96.86% - 99.58%

Color and Shape: Solid

Molecular weight: 515.52

Ref: TM-T1145

bis(2-acetamidoacetic acid); 4-[(2E)-3-(4-carbamimidoylphenyl)triaz-2-en-1-yl]benzene-1-carboximidamide

CAS: 908-54-3

Formula: C₂₂H₂₉N₉O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 515.5224

Ref: IN-DA00IGAM

Diminazene Aceturate

CAS: 908-54-3

Diminazene Aceturate

Formula: C₂₂H₂₉N₉O₆

Purity: ≥95%

Molecular weight: 515.52

Ref: 54-BUP17354

Diminazene Aceturate

CAS: 908-54-3

Formula: C₁₄H₁₅N₇·2C₄H₇NO₃

Color and Shape: Yellow Solid

Molecular weight: 281.32 2*117.10

Ref: 4Z-D-531

Diminazene diaceturate

CAS: 908-54-3

Formula: C₁₄H₁₅N₇·2C₄H₇NO₃

Purity: (UV) ≥ 95.0%

Color and Shape: Pale yellow powder to dark yellow-orange powder

Molecular weight: 515.52

Ref: 7W-GA5509

Diminazene aceturate

CAS: 908-54-3

Formula: C₁₄H₁₅N₇C₄H₇NO₃

Color and Shape: Neat

Molecular weight: 515.52

Ref: 04-C12773000

Diminazene 1000 µg/mL in Acetonitrile:Water

Controlled Product

CAS: 908-54-3

Formula: C₁₄H₁₅N₇C₄H₇NO₃

Color and Shape: Colourless

Molecular weight: 515.52

Ref: 04-A12772990WL-1000

Diminazene Diaceturate

Controlled Product

CAS: 908-54-3

Applications Diminazene Diaceturate is an anti-protozoal drug. Diminazene Diaceturate is used as an anti-trypanosomal agent.
References Kellner, H. et al.: Trop. Med. Parasitol., 36, 199 (1985); Merschjohann, K. et al.: Exp. Parasitol., 118, 637 (2008);

Formula: C₁₄H₁₅N₇·2C₄H₇NO₃

Color and Shape: Neat

Molecular weight: 515.52

Ref: TR-D479720

Diminazene diaceturate

CAS: 908-54-3

Diminazene diaceturate is a cytotoxic drug that inhibits the polymerase chain reaction and blocks mitochondrial membrane potential. It has been shown to be effective in vitro method against HL-60 cells, which are human leukemia cells. Diminazene diaceturate also leads to c-jun phosphorylation and diminazene aceturate, which is a metabolite of the drug. The optimum concentration for this drug is determined by dextran sulfate, which can be used as an energy source for the cell. This drug has been shown to have cardiac effects in rats.

Formula: C₂₂H₂₉N₉O₆

Purity: Min. 95%

Molecular weight: 515.52 g/mol

Ref: 3D-FD30274

Diminazene Diaceturate

CAS: 908-54-3

Formula: C₁₄H₁₅N₇(C₄H₇NO₃)

Molecular weight: 281.32 : 2(117.10)

Ref: ST-EA-CP-D189000