CAS 909910-43-6

3-(6-methylpyridin-2-yl)-N-phenyl-4-quinolin-4-yl-1H-pyrazole-1-carbothioamide

Description:

3-(6-methylpyridin-2-yl)-N-phenyl-4-quinolin-4-yl-1H-pyrazole-1-carbothioamide, with the CAS number 909910-43-6, is a complex organic compound characterized by its diverse functional groups and structural features. This compound contains a pyrazole core, which is a five-membered ring known for its biological activity, and is substituted with a carbothioamide group, enhancing its potential reactivity and interaction with biological targets. The presence of a quinoline moiety contributes to its aromatic character and may influence its solubility and stability. Additionally, the 6-methylpyridine substituent introduces a nitrogen atom into the structure, which can participate in hydrogen bonding and coordination with metal ions. The phenyl group attached to the nitrogen atom of the pyrazole adds to the overall hydrophobic character of the molecule. Such structural characteristics suggest that this compound may exhibit interesting pharmacological properties, making it a candidate for further investigation in medicinal chemistry and drug development. Its unique combination of heterocycles and functional groups may also allow for diverse applications in various chemical and biological contexts.

Formula: C₂₅H₁₉N₅S

InChI: InChI=1/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)

SMILES: Cc1cccc(c2c(cn(C(=Nc3ccccc3)S)n2)c2ccnc3ccccc23)n1

Synonyms:

• A83-01

A 83-01

CAS: 909910-43-6

Formula: C₂₅H₁₉N₅S

Purity: >95.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 421.52

Ref: 3B-A3324

A 83-01

CAS: 909910-43-6

A 83-01

Purity: ≥95%

Molecular weight: 421.52g/mol

Ref: 54-BUP13303

A 83-01 [Optimized for Cell Culture]

CAS: 909910-43-6

Formula: C₂₅H₁₉N₅S

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 421.52

Ref: 3B-A3679

A 83-01

CAS: 909910-43-6

Formula: C₂₅H₁₉N₅S

Molecular weight: 421.52

Ref: 4Z-K-031009

A 83-01

CAS: 909910-43-6

A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7.

Formula: C₂₅H₁₉N₅S

Purity: 97% - 98.2%

Color and Shape: Solid

Molecular weight: 421.52

Ref: TM-T3031

A 83-01

Controlled Product

CAS: 909910-43-6

Stability Moisture Sensitive
Applications A 83-01 is a selective inhibitor of TGF-β type I receptor. A 83-01 treatment increases tumor permeability.
References Minowa, T. et al.: British. J. Canc., 101, 1884 (2009)

Formula: C₂₅H₁₉N₅S

Color and Shape: Off-White

Molecular weight: 421.52

Ref: TR-A101210

A 83-01

CAS: 909910-43-6

Potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7. Inhibits differentiation of rat induced pluripotent stem cells (riPSCs) and increases clonal expansion efficiency. Helps maintain homogeneity and long-term in vitro self-renewal of human iPSCs.

Formula: C₂₅H₁₉N₅S

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 421.52 g/mol

Ref: 3D-BA162484