CAS 91161-71-6

Terbinafine

Description:

Terbinafine is an antifungal medication primarily used to treat fungal infections, particularly those affecting the skin and nails, such as athlete's foot, ringworm, and onychomycosis. It belongs to the allylamine class of antifungals and works by inhibiting the enzyme squalene epoxidase, which is crucial in the biosynthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to cell death and effectively clears the infection. Terbinafine is available in various forms, including oral tablets and topical creams or gels. It is generally well-tolerated, but potential side effects may include gastrointestinal disturbances, skin reactions, and, in rare cases, liver toxicity. The drug is contraindicated in individuals with liver disease and should be used with caution in those with renal impairment. Terbinafine has a relatively long half-life, allowing for once-daily dosing in oral formulations, which enhances patient compliance. Overall, its efficacy and safety profile make it a widely used option in antifungal therapy.

Formula: C₂₁H₂₅N

InChI: InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+

InChI key: InChIKey=DOMXUEMWDBAQBQ-WEVVVXLNSA-N

SMILES: C(N(C/C=C/C#CC(C)(C)C)C)C=1C2=C(C=CC1)C=CC=C2

Synonyms:

• 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-
• Da 5505
• Daskil
• Eksifine
• Fungoterbin
• Lamasil
• Mycoterbin
• N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine
• Sf 86-327
• Tdt 067
• Tebina
• Terbinafine
• Terbinol
• Terbisil
• Yy 1084
• trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine

Terbinafine

CAS: 78628-80-5, 91161-71-6

Formula: C₂₁H₂₅N

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 291.44

Ref: 3B-T3677

Terbinafine Hydrochloride

CAS: 78628-80-5, 91161-71-6

Formula: C₂₁H₂₅N·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 327.90

Ref: 3B-D2049

N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine

CAS: 91161-71-6

Formula: C₂₁H₂₅N

Purity: 98%

Color and Shape: Solid

Molecular weight: 291.4299

Ref: IN-DA0039UM

Terbinafine

CAS: 91161-71-6

Formula: C₂₁H₂₅N

Molecular weight: 291.44

Ref: 4Z-T-5414

Terbinafine

CAS: 91161-71-6

Terbinafine

Purity: ≥98%

Molecular weight: 291.43g/mol

Ref: 54-BUP14870

(2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine

CAS: 91161-71-6

(2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine

Purity: 98%

Color and Shape: Solid

Molecular weight: 291.43g/mol

Ref: 54-OR72060

Terbinafine

CAS: 91161-71-6

Terbinafine, an allylamine, blocks ergosterol synthesis via squalene epoxidase, inhibiting fungal growth.

Formula: C₂₁H₂₅N

Purity: 99.9% - >99.99%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 291.43

Ref: TM-T6702

Terbinafine

CAS: 91161-71-6

Applications Terbinafine is used to treat infections caused by a fungus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₂₁H₂₅N

Color and Shape: White To Off-White

Molecular weight: 291.43

Ref: TR-T107513

Terbinafine base

CAS: 91161-71-6

Activator of the two-pore domain potassium channel TASK3

Formula: C₂₁H₂₅N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 291.43 g/mol

Ref: 3D-FT31807

Terbinafine

CAS: 91161-71-6

Purity: 98%

Molecular weight: 291.44

Ref: 10-F375847