CAS 91161-71-6
:Terbinafine
Description:
Terbinafine is an antifungal medication primarily used to treat fungal infections, particularly those affecting the skin and nails, such as athlete's foot, ringworm, and onychomycosis. It belongs to the allylamine class of antifungals and works by inhibiting the enzyme squalene epoxidase, which is crucial in the biosynthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to cell death and effectively clears the infection. Terbinafine is available in various forms, including oral tablets and topical creams or gels. It is generally well-tolerated, but potential side effects may include gastrointestinal disturbances, skin reactions, and, in rare cases, liver toxicity. The drug is contraindicated in individuals with liver disease and should be used with caution in those with renal impairment. Terbinafine has a relatively long half-life, allowing for once-daily dosing in oral formulations, which enhances patient compliance. Overall, its efficacy and safety profile make it a widely used option in antifungal therapy.
Formula:C21H25N
InChI:InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
InChI key:InChIKey=DOMXUEMWDBAQBQ-WEVVVXLNSA-N
SMILES:C(N(C/C=C/C#CC(C)(C)C)C)C=1C2=C(C=CC1)C=CC=C2
Synonyms:- 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-
- 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-
- Da 5505
- Daskil
- Eksifine
- Fungoterbin
- Lamasil
- Mycoterbin
- N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine
- Sf 86-327
- Tdt 067
- Tebina
- Terbinafine
- Terbinol
- Terbisil
- Yy 1084
- trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine
- See more synonyms
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Terbinafine
CAS:Formula:C21H25NPurity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:291.44(2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
CAS:(2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amineFormula:C21H25NPurity:98%Color and Shape:SolidMolecular weight:291.42989Terbinafine (Standard)
CAS:Terbinafine (Standard) is the standard substance of Terbinafine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.Formula:C21H25NMolecular weight:291.4299N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine
CAS:Formula:C21H25NPurity:98%Color and Shape:SolidMolecular weight:291.4299Terbinafine
CAS:Applications Terbinafine is used to treat infections caused by a fungus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormula:C21H25NColor and Shape:NeatMolecular weight:291.43Terbinafine
CAS:Terbinafine, an allylamine, blocks ergosterol synthesis via squalene epoxidase, inhibiting fungal growth.Formula:C21H25NPurity:99.90% - >99.99%Color and Shape:White SolidMolecular weight:291.4299Terbinafine
CAS:(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amineFormula:C21H25NPurity:98%Molecular weight:291.42Terbinafine base
CAS:Activator of the two-pore domain potassium channel TASK3
Formula:C21H25NPurity:Min. 95%Color and Shape:PowderMolecular weight:291.43 g/mol
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