CAS: 91421-42-0 - Rubitecan

Formula: C₂₀H₁₅N₃O₆

InChI: InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1

InChI key: InChIKey=VHXNKPBCCMUMSW-FQEVSTJZSA-N

SMILES: O=C1OCC=2C(=O)N3C(=CC2C1(O)CC)C=4N=C5C=CC=C(C5=CC4C3)N(=O)=O

Synonyms:

• (4R)-4-ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-10-nitro-, (4S)-
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-10-nitro-, (S)-
• 4-ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 9-Nitro-20(S)-camptothecin
• 9-Nitrocamptothecin
• 9-Nitrocellulose camptothecine
• Orathecin
• Rfs 2000

Rubitecan

CAS: 91421-42-0

• Formula: C₂₀H₁₅N₃O₆
• Purity: ≥98.0%(HPLC)
• Color and Shape: Solid
• Molecular weight: 393.3496

Rubitecan

CAS: 91421-42-0

• Formula: C₂₀H₁₅N₃O₆
• Molecular weight: 393.35

Rubitecan

CAS: 91421-42-0

• Formula: C₂₀H₁₅N₃O₆
• Purity: 95%~99%
• Molecular weight: 393.355

9-Nitrocamptothecin

CAS: 91421-42-0

• Formula: C₂₀H₁₅N₃O₆
• Purity: >98.0%(HPLC)
• Color and Shape: White to Yellow powder to crystal
• Molecular weight: 393.36

Rubitecan

CAS: 91421-42-0

Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases …

• Formula: C₂₀H₁₅N₃O₆
• Purity: 98%
• Color and Shape: Yellow Amorphous Powder
• Molecular weight: 393.35

Rubitecan

CAS: 91421-42-0

Topoisomerase I inhibitor

• Formula: C₂₀H₁₅N₃O₆
• Purity: Min. 95%
• Molecular weight: 393.35 g/mol

Rubitecan

CAS: 91421-42-0

Applications Semisynthetic camptothecin which inhibits DNA topoisomerase I. Prodrug of 9-aminocamptothecin. Antineoplastic. References Stehlin, J.S., …

• Formula: C₂₀H₁₅N₃O₆
• Color and Shape: Yellow Solid
• Molecular weight: 393.35