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CAS 91503-79-6

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Flurbiprofen axetil

Description:
Flurbiprofen axetil is a prodrug of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic and anti-inflammatory properties. As a prodrug, flurbiprofen axetil is designed to enhance the solubility and bioavailability of flurbiprofen, allowing for improved absorption in the body. The substance is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. Flurbiprofen axetil is typically administered orally and is known for its relatively rapid conversion to the active form, flurbiprofen, after metabolism. The compound exhibits a favorable pharmacokinetic profile, including a moderate half-life, which allows for effective pain management in various conditions, such as arthritis and postoperative pain. Additionally, it is important to consider potential side effects, which may include gastrointestinal discomfort, cardiovascular risks, and renal impairment, similar to other NSAIDs. Overall, flurbiprofen axetil represents a valuable option in the management of pain and inflammation.
Formula:C19H19FO4
InChI:InChI=1S/C19H19FO4/c1-12(19(22)24-14(3)23-13(2)21)16-9-10-17(18(20)11-16)15-7-5-4-6-8-15/h4-12,14H,1-3H3
InChI key:InChIKey=ALIVXCSEERJYHU-UHFFFAOYSA-N
SMILES:FC1=C(C=CC(C(C(OC(OC(C)=O)C)=O)C)=C1)C2=CC=CC=C2
Synonyms:
  • (±)-2-Fluoro-alpha-methyl-4-biphenylacetic acid 1-(acetoxy)ethyl ester
  • 1-(Acetyloxy)Ethyl 2-(2-Fluorobiphenyl-4-Yl)Propanoate
  • 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate
  • 1-Acetoxyethyl 2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanoate
  • Flurbiprofen axetil
  • Fp-83
  • Lfp 83
  • Ropion
  • Ropiopn
  • [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 1-(acetyloxy)ethyl ester
  • [1,​ 1'-​ Biphenyl]​ -​ 4-​ acetic acid, 2-​ fluoro-​ α-​ methyl-​ , 1-​ (acetyloxy)​ ethyl ester
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Found 11 products.
  • 1-Acetoxyethyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate

    CAS:
    Formula:C19H19FO4
    Purity:98%
    Color and Shape:Liquid
    Molecular weight:330.3502

    Ref: IN-DA0036RM

    1g
    630.00€
    100mg
    115.00€
    250mg
    188.00€
  • Flurbiprofen Axetil (Mixture of Diastereomers)

    CAS:
    Formula:C19H19FO4
    Color and Shape:Colorless Clear Liquid
    Molecular weight:330.36

    Ref: 4Z-F-0813

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Flurbiprofen Axetil

    CAS:
    Flurbiprofen Axetil
    Purity:≥95%
    Molecular weight:330.35g/mol

    Ref: 54-BUP13683

    1g
    626.00€
    10mg
    53.00€
    25mg
    93.00€
    50mg
    149.00€
    100mg
    220.00€
    200mg
    313.00€
  • 1-(Acetyloxy)ethyl 2-(2-fluorobiphenyl-4-yl)propanoate

    CAS:
    <p>1-(Acetyloxy)ethyl 2-(2-fluorobiphenyl-4-yl)propanoate</p>
    Purity:99%
    Molecular weight:330.35g/mol

    Ref: 54-PC402065

    1g
    421.00€
    5g
    1,476.00€
    100mg
    96.00€
    250mg
    199.00€
  • Flurbiprofen axetil

    CAS:
    Formula:C15H13FO2
    Molecular weight:244.26

    Ref: 7W-GP5297

    ne
    To inquire
  • Flurbiprofen Axetil-13C-d3

    CAS:
    Formula:CC18H16D3FO4
    Molecular weight:334.37

    Ref: 4Z-F-0826

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Flurbiprofen Axetil

    CAS:
    <p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>
    Formula:C19H19FO4
    Purity:97.58% - 98%
    Color and Shape:Solid
    Molecular weight:330.35
  • 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate

    CAS:
    <p>1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate is a synthetic analog of flurbiprofen that has potent nonsteroidal anti-inflammatory drug activity. It binds to the same receptor as flurbiprofen, but with a higher affinity. 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate is used for the treatment of postoperative pain and inflammation following abdominal surgery. This compound is also used for the prevention of ischemic brain damage after cardiac bypass surgery or other types of vascular surgery, such as carotid endarterectomy. 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate can be synthesized by reacting bisphenol A with carbonyldiimidazole and 4-[2-(2,4 -difluorophenyl)-</p>
    Formula:C19H19FO4
    Purity:Min. 95%
    Color and Shape:Orange Powder
    Molecular weight:330.35 g/mol

    Ref: 3D-FA23508

    10mg
    154.00€
    25mg
    219.00€
    50mg
    335.00€
    100mg
    477.00€
    250mg
    807.00€
  • 1-Acetoxyethyl 2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanoate

    CAS:
    Formula:C19H19FO4
    Purity:99%
    Molecular weight:330.355

    Ref: 10-F463587

    1g
    603.00€
    100mg
    124.00€
    250mg
    256.00€
  • Flurbiprofen Axetil

    Controlled Product
    CAS:
    <p>Applications An anti-inflammatory used as an analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chalmers, et al.: Ann. Rheum. Dis., 31, 319 (1972), Nishizawa, et al.: Thromb. Res., 3, 577 (1973)<br></p>
    Formula:C19H19FO4
    Color and Shape:Neat
    Molecular weight:330.35

    Ref: TR-F598710

    100mg
    213.00€
    500mg
    694.00€
  • Flurbiprofen Axetil (Mixture of Diastereomers)

    CAS:
    Formula:C19H19FO4
    Molecular weight:330.36

    Ref: ST-EA-CP-F141017

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire