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CAS 91503-79-6

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Flurbiprofen axetil

Description:
Flurbiprofen axetil is a prodrug of flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic and anti-inflammatory properties. As a prodrug, flurbiprofen axetil is designed to enhance the solubility and bioavailability of flurbiprofen, allowing for improved absorption in the body. The substance is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. Flurbiprofen axetil is typically administered orally and is known for its relatively rapid conversion to the active form, flurbiprofen, after metabolism. The compound exhibits a favorable pharmacokinetic profile, including a moderate half-life, which allows for effective pain management in various conditions, such as arthritis and postoperative pain. Additionally, it is important to consider potential side effects, which may include gastrointestinal discomfort, cardiovascular risks, and renal impairment, similar to other NSAIDs. Overall, flurbiprofen axetil represents a valuable option in the management of pain and inflammation.
Formula:C19H19FO4
InChI:InChI=1S/C19H19FO4/c1-12(19(22)24-14(3)23-13(2)21)16-9-10-17(18(20)11-16)15-7-5-4-6-8-15/h4-12,14H,1-3H3
InChI key:InChIKey=ALIVXCSEERJYHU-UHFFFAOYSA-N
SMILES:FC1=C(C=CC(C(C(OC(OC(C)=O)C)=O)C)=C1)C2=CC=CC=C2
Synonyms:
  • (±)-2-Fluoro-alpha-methyl-4-biphenylacetic acid 1-(acetoxy)ethyl ester
  • 1-(Acetyloxy)Ethyl 2-(2-Fluorobiphenyl-4-Yl)Propanoate
  • 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate
  • 1-Acetoxyethyl 2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanoate
  • Flurbiprofen axetil
  • Fp-83
  • Lfp 83
  • Ropion
  • Ropiopn
  • [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 1-(acetyloxy)ethyl ester
  • [1,​ 1'-​ Biphenyl]​ -​ 4-​ acetic acid, 2-​ fluoro-​ α-​ methyl-​ , 1-​ (acetyloxy)​ ethyl ester
Found 13 products.