CAS 915124-86-6
:Telmisartan Amide
Description:
Telmisartan Amide is a chemical compound that belongs to the class of angiotensin II receptor antagonists, primarily used in the treatment of hypertension and cardiovascular diseases. It is a derivative of telmisartan, which is known for its ability to block the action of angiotensin II, a hormone that constricts blood vessels and raises blood pressure. The amide functional group in Telmisartan Amide contributes to its pharmacological properties, enhancing its binding affinity to the angiotensin receptor. This compound typically exhibits good solubility in organic solvents and moderate stability under standard conditions. Its molecular structure includes a biphenyl moiety, which is characteristic of many antihypertensive agents, and it may also possess lipophilic properties that facilitate its absorption and distribution in biological systems. As with many pharmaceuticals, the safety and efficacy of Telmisartan Amide are evaluated through clinical studies, and it is essential to consider potential side effects and interactions with other medications when used in therapeutic settings.
Formula:C33H31N5O
InChI:InChI=1S/C33H31N5O/c1-4-9-30-36-31-21(2)18-24(33-35-27-12-7-8-13-28(27)37(33)3)19-29(31)38(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)32(34)39/h5-8,10-19H,4,9,20H2,1-3H3,(H2,34,39)
InChI key:YAIWQMXHIQDCFT-UHFFFAOYSA-N
SMILES:CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)N)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
Synonyms:- [1,1'-Biphenyl]-2-carboxamide, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-
- 4'-[(1,7'-Dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]-2-biphenylcarboxamide
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TELMISARTAN FOR SYSTEM SUITABILITY CRS
CAS:TELMISARTAN FOR SYSTEM SUITABILITY CRSFormula:C33H30N4O2Color and Shape:PowderMolecular weight:514.6169Telmisartan EP Impurity F
CAS:Formula:C33H31N5OColor and Shape:White To Off-White SolidMolecular weight:513.654'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxamide
CAS:4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxamideFormula:C33H31N5OPurity:99%Molecular weight:513.654′-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl][1,1′-biphenyl]-2-carboxamide (Telmisartan Amide)
CAS:Formula:C33H31N5OColor and Shape:NeatMolecular weight:513.63PPARγ agonist 5
CAS:PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.Formula:C33H31N5OColor and Shape:SolidMolecular weight:513.63Telmisartan Amide
CAS:Impurity Telmisartan EP Impurity F / Telmisartan Amide
Applications An amide impurity of Temisartan (D294250).
References Xu, G. et al.: Zhong. Yiyao Gong. Zaz., 40, 714 (2009);Formula:C33H31N5OColor and Shape:NeatMolecular weight:513.634'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxamide
CAS:Formula:C33H31N5OPurity:99%Molecular weight:513.634'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxamide
CAS:Imatinib is a drug substance that belongs to the class of imidazole and phenylpiperidine derivatives. It is used in the treatment of leukemia and other cancers. Imatinib has been shown to inhibit tumor cell proliferation by inhibiting protein synthesis via inhibition of ribosomal activity, leading to cell death. Imatinib also inhibits the activation of PPARγ, an important transcription factor involved in lipid metabolism. The presence of impurities may affect the therapeutic efficacy or safety of this drug, so it is important to know what impurities are present in order to avoid unexpected side effects.Formula:C33H31N5OPurity:Min. 95%Molecular weight:513.63 g/mol
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