CAS 91809-66-4

5-Carboxytetramethylrhodamine

Description:

5-Carboxytetramethylrhodamine (often abbreviated as TMR or TMR-C) is a fluorescent dye belonging to the rhodamine family, characterized by its vibrant red fluorescence. It is commonly used in various biological and chemical applications, particularly in fluorescence microscopy and flow cytometry due to its high quantum yield and photostability. The presence of a carboxylic acid group enhances its solubility in aqueous solutions, making it suitable for labeling biomolecules such as proteins and nucleic acids. The dye exhibits strong absorption in the green region of the spectrum and emits light in the red region, allowing for effective separation from other fluorescent markers. Additionally, its ability to form conjugates with amines and other reactive groups makes it versatile for various labeling techniques. Overall, 5-Carboxytetramethylrhodamine is a valuable tool in molecular biology and biochemistry for tracking and visualizing cellular processes.

Formula: C₂₅H₂₂N₂O₅

InChI: InChI=1/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)

SMILES: CN(C)c1ccc2c(c1)[o+]c1cc(ccc1c2c1ccc(cc1C(=O)[O-])C(=O)O)N(C)C

Synonyms:

• 5-Carboxytetramethylrhodamine*(Single Isomer)
• 5-Tamra
• 3-carboxy-4-[6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]benzoate

5-TAMRA

CAS: 91809-66-4

5-TAMRA

Formula: C₂₅H₂₂N₂O₅

Purity: ≥98%

Molecular weight: 430.45

Ref: 54-BUP11101

5-Carboxytetramethylrhodamine

CAS: 91809-66-4

Formula: C₂₅H₂₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 430.4526

Ref: IN-DA00GRM1

5-Carboxytetramethylrhodamine

CAS: 91809-66-4

5-Carboxytetramethylrhodamine

Formula: C₂₅H₂₂N₂O₅

Purity: 98%

Color and Shape: Solid-Powder

Molecular weight: 430.45257

Ref: 54-BIB6287

5-TAMRA

CAS: 91809-66-4

Formula: C₂₅H₂₂N₂O₅

Purity: >95.0%(T)(HPLC)

Color and Shape: Green to Dark green powder to crystal

Molecular weight: 430.46

Ref: 3B-C2686

5-Carboxytetramethylrhodamine

CAS: 91809-66-4

Formula: C₂₅H₂₂N₂O₅

Molecular weight: 430.46

Ref: 7W-GT5624

5-TAMRA

CAS: 91809-66-4

5-TAMRA (5-Carboxytetramethylrhodamine) (5-Carboxytetramethylrhodamine) yields bright, pH-insensitive orange-red fluorescence (approximate excitation/emission

Formula: C₂₅H₂₂N₂O₅

Purity: 99.79% - 99.85%

Color and Shape: Brown Solid

Molecular weight: 430.45

Ref: TM-T18891

5-Carboxytetramethylrhodamine

CAS: 91809-66-4

5-Carboxytetramethylrhodamine - (TAMRA) is a widely employed fluorescent dye (orange/red) that is suitable for different uses. In PCR applications, it has been used as both a reporter at the 5’ or as a quencher at the 3’ end. TAMRA-labelled oligonucleotides have been used to study interactions with DNA or DNA/protein interactions. It is an excellent fluorescent acceptor for FRET applications with a suitable dye pair. It is used as a protein/antibody labelling agent for structural studies, immunochemistry and flow cytometry. Bioconjugation is generally performed through coupling of the carboxylic acid to a primary amine at the N-terminus of a protein, on lysine side chains or amino-modified oligonucleotide.

Formula: C₂₅H₂₂N₂O₅

Purity: Min. 95 Area-%

Color and Shape: Green Powder

Molecular weight: 430.45 g/mol

Ref: 3D-FC19806

2-(3,6-Bis(dimethylamino)xanthylium-9-yl)-5-carboxybenzoate

CAS: 91809-66-4

Formula: C₂₅H₂₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 430.46

Ref: 10-F361981

5-Carboxytetramethyl Rhodamine Monohydrochloride

Controlled Product

CAS: 91809-66-4

Applications A long-wavelength dye.
References Singleton, D., et al.: J. Med. Chem., 50, 2931 (2007), Dose, C., et al.: Bioorg. Med. Chem., 16, 65 (2008),

Formula: C₂₅H₂₂N₂O₅·HCl

Color and Shape: Neat

Molecular weight: 430.5

Ref: TR-C183150