CAS 92122-45-7

Fmoc-D-Lys(Boc)-OH

Description:

Fmoc-D-Lys(Boc)-OH, with the CAS number 92122-45-7, is a protected amino acid commonly used in peptide synthesis. It features a D-lysine backbone, which is an essential building block in the formation of peptides and proteins. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino function, allowing for selective reactions during synthesis. The Boc (tert-butyloxycarbonyl) group protects the side chain amino group of lysine, providing stability and preventing unwanted reactions. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under standard laboratory conditions makes it suitable for various applications in organic synthesis and biochemistry. The use of Fmoc and Boc protecting groups allows for the stepwise assembly of peptides, facilitating the synthesis of complex structures while maintaining the integrity of the amino acid side chains.

Formula: C₃₆H₃₄N₂O₆

InChI: InChI=1/C36H34N2O6/c39-34(40)33(38-36(42)44-22-32-29-17-7-3-13-25(29)26-14-4-8-18-30(26)32)19-9-10-20-37-35(41)43-21-31-27-15-5-1-11-23(27)24-12-2-6-16-28(24)31/h1-8,11-18,31-33H,9-10,19-22H2,(H,37,41)(H,38,42)(H,39,40)/t33-/m1/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=NCCCC[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Synonyms:

• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-epsilon-t-butyl-oxycarbonyl-D-lysine
• N2,N6-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine

Nε-(tert-Butoxycarbonyl)-Nα-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine

CAS: 92122-45-7

Formula: C₂₆H₃₂N₂O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 468.55

Ref: 3B-B3071

N(ε)-Boc-N(α)-Fmoc-D-lysine, 98%

CAS: 92122-45-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₆H₃₂N₂O₆

Purity: 98%

Color and Shape: Powder, White

Molecular weight: 468.55

Ref: 02-H28301

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

Bachem ID: 4004439.

Formula: C₂₆H₃₂N₂O₆

Purity: 99.9%

Color and Shape: White

Molecular weight: 468.55

Ref: 01-4004439

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

Formula: C₂₆H₃₂N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.5421

Ref: IN-DA006I0U

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

Fmoc-D-Lys(Boc)-OH

Purity: 98%

Molecular weight: 468.54g/mol

Ref: 54-OR36374

Lysine Impurity 16 (Fmoc-D-Lys(Boc)-OH)

CAS: 92122-45-7

Formula: C₂₆H₃₂N₂O₆

Molecular weight: 468.55

Ref: 4Z-L-138054

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

Formula: C₂₆H₃₂N₂O₆

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 468.54

Ref: 7W-GM4759

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

Fmoc-D-Lys(Boc)-OH is a building block for the synthesis of peptides. It can be used to synthesize chains that are up to 17 amino acids long. Fmoc-D-Lys(Boc)-OH is a protected amino acid with an active group on the alpha carbon and has been used in the synthesis of ganirelix acetate, a peptide that is used in the treatment of prostate cancer. The Boc group is an organic compound that protects the lysine side chain from reacting with other compounds. The Fmoc group is also an organic compound, which helps to protect the side chain from reactions with other compounds. These groups are removed at different stages of synthesis, depending on what type of reaction needs to take place next.

Formula: C₂₆H₃₂N₂O₆

Purity: Min. 95%

Molecular weight: 468.55 g/mol

Ref: 3D-FDK-1815-PI

Fmoc-D-Lys(Boc)-OH

CAS: 92122-45-7

M03424 - Fmoc-D-Lys(Boc)-OH

Formula: C₂₆H₃₂N₂O₆

Purity: 98%

Color and Shape: White powder

Molecular weight: 468.55

Ref: 10-M03424

N6-​[(1,​1-​Dimethylethoxy)​carbonyl]​-​N2-​[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​-D-​lysine

Controlled Product

CAS: 92122-45-7

Applications Derivative of N6-​[(1,​1-​Dimethylethoxy)​carbonyl]​-​N2-​[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​-D-​lysine is a hetero-bifunctional traceless linker for temporarily attaching highly solubilizing peptide sequences onto insoluble peptides.
References Jacobsen, M., et al.: J. Am. Chem. Soc., 138, 11775-11782 (2016)

Formula: C₂₆H₃₂N₂O₆

Color and Shape: Neat

Molecular weight: 468.54

Ref: TR-D447255

N-alpha-Fmoc-Nepsilon-Boc-D-lysine

CAS: 92122-45-7

N-alpha-Fmoc-Nepsilon-Boc-D-lysine is a synthetic amino acid that is used for the treatment of bacterial, fungal, and cancer cells. It has been shown to induce apoptosis in cancer cells by increasing the mitochondrial membrane potential and reducing the cellular uptake of glucose. This drug also increases the production of reactive oxygen species in cancer cells, which can lead to cancer cell death. N-alpha-Fmoc-Nepsilon-Boc-D-lysine has been shown to have synergistic anticancer effects when combined with other drugs, such as antibiotics or antimicrobial peptides. NAPBODA has a high affinity for bacterial membranes and can be used as an antimicrobial agent.

Formula: C₂₆H₃₂N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 468.54 g/mol

Ref: 3D-FF47343