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CAS 923-61-5

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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

Description:
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) is a phospholipid commonly used in biochemistry and cell biology. It is characterized by its two palmitic acid chains, which are saturated fatty acids, contributing to its hydrophobic properties. The molecule features a glycerol backbone esterified to two fatty acid chains at the first and second positions, while the third position is linked to a phosphoethanolamine group. This structure imparts amphiphilic characteristics, allowing DPPE to form bilayers and vesicles in aqueous environments, making it essential in membrane studies and drug delivery systems. DPPE is often utilized in liposome formulation and as a component in lipid bilayers for various applications, including the study of membrane dynamics and protein interactions. Its stability and compatibility with biological systems make it a valuable tool in research and pharmaceutical development. Additionally, DPPE can participate in various biochemical reactions, including those involving membrane fusion and cellular signaling pathways.
Formula:C37H74NO8P
InChI:InChI=1/C37H74NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(39)43-33-35(34-45-47(41,42)44-32-31-38)46-37(40)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h35H,3-34,38H2,1-2H3,(H,41,42)/t35-/m1/s1
InChI key:InChIKey=SLKDGVPOSSLUAI-PGUFJCEWSA-N
SMILES:[C@@H](OC(CCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O
Synonyms:
  • (2R)-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexadecanoyloxy)propyl hexadecanoate
  • (R)-Dipalmitoylphosphatidylethanolamine
  • 1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylethanolamine
  • 1,2-Dipalmitoyl-3-sn-phosphatidylethanolamine
  • 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-3-phosphatidylethanolamine
  • 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylethanolamine
  • 1,2-Dipalmitoyl-L-3-phosphatidylethanolamine
  • 1,2-Dipalmitoyl-L-a-phosphatidylethanolamine
  • 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-Ethanolamine
  • 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylethanolamine
  • See more synonyms
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