CAS: 923564-51-6 - ABT 263

Formula: C₄₇H₅₅ClF₃N₅O₆S₃

InChI: InChI=1S/C47H55ClF3N5O6S3/c1-46(2)20-18-42(34-8-12-37(48)13-9-34)36(31-46)32-55-22-24-56(25-23-55)39-14-10-35(11-15-39)45(57)53-65(60,61)41-16-17-43(44(30-41)64(58,59)47(49,50)51)52-38(19-21-54-26-28-62-29-27-54)33-63-40-6-4-3-5-7-40/h3-17,30,38,52H,18-29,31-33H2,1-2H3,(H,53,57)/t38-/m1/s1

InChI key: InChIKey=JLYAXFNOILIKPP-KXQOOQHDSA-N

SMILES: O=C(NS(=O)(=O)C1=CC=C(NC(CSC=2C=CC=CC2)CCN3CCOCC3)C(=C1)S(=O)(=O)C(F)(F)F)C4=CC=C(C=C4)N5CCN(CC6=C(C=7C=CC(Cl)=CC7)CCC(C)(C)C6)CC5

Synonyms:

• 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
• A 855071.0
• Abt-263
• Benzamide, 4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-
• Navitoclax

4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide

CAS: 923564-51-6

• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 974.6127

Navitoclax

CAS: 923564-51-6

View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein …

• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• Purity: 100% - 99.67%
• Color and Shape: Pale Yellow Solid
• Molecular weight: 974.61

ABT 263

CAS: 923564-51-6

Applications A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate. Potent …

• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• Color and Shape: Neat
• Molecular weight: 974.61

Navitoclax

CAS: 923564-51-6

A Bad-like BH3 mimetic with strong affinity for Bcl-xl, Bcl-2 and Bcl-w that promotes BIM-mediated …

• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 974.62 g/mol

Navitoclax

CAS: 923564-51-6

Please enquire for more information about Navitoclax including the price, delivery time and more detailed …

• Formula: C₄₇H₅₅ClF₃N₅O₆S₃
• Purity: Min. 95%
• Molecular weight: 974.62 g/mol