CAS 927880-90-8
:RAF 265
Description:
RAF 265, with the CAS number 927880-90-8, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential as a therapeutic agent. It is classified as a small molecule inhibitor, specifically targeting certain kinases involved in cellular signaling pathways. The compound exhibits properties that may contribute to its efficacy in treating various diseases, including cancer. RAF 265 is known for its ability to inhibit the activity of the RAF kinase family, which plays a crucial role in the MAPK/ERK signaling pathway, often implicated in tumorigenesis. In terms of its physical characteristics, RAF 265 is typically presented as a solid at room temperature, with specific solubility and stability profiles that are relevant for formulation in pharmaceutical applications. Its development has been part of ongoing research aimed at understanding its pharmacokinetics, bioavailability, and overall therapeutic potential. As with many investigational compounds, further studies are essential to fully elucidate its safety and efficacy in clinical settings.
Formula:C24H16F6N6O
Synonyms:- 1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
- Chir 265
- Raf265
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Found 7 products.
RAF265
CAS:1-Methyl-5-((2-(5-(trifluoromethyl)-1H-imidazol-2-yl)pyridin-4-yl)oxy)-N-(4-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-amineFormula:C24H16F6N6OPurity:99%Molecular weight:518.41RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:White SolidMolecular weight:518.41Ref: TM-T6296
1mg44.00€2mg59.00€5mg93.00€1mL*10mM (DMSO)94.00€10mg140.00€25mg253.00€50mg413.00€100mg605.00€
