CAS 928672-86-0

Canagliflozin hemihydrate

Description:

Canagliflozin hemihydrate is a pharmaceutical compound primarily used as an antidiabetic medication for the management of type 2 diabetes mellitus. It belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors, which function by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The hemihydrate form indicates that the compound contains half a molecule of water for each molecule of canagliflozin, which can influence its solubility and stability. Canagliflozin is characterized by its specific molecular structure, which includes a substituted phenyl ring and a glucoside moiety, contributing to its pharmacological activity. The compound is typically administered orally and is known to have additional benefits, such as weight loss and cardiovascular protection. As with any medication, it is essential to consider potential side effects and contraindications, and it should be used under medical supervision.

Formula: C₂₄H₂₅FO₅S.1/2H₂O

Synonyms:

• D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, hydrate (2:1), (1S)-

Canagliflozin Hemihydrate INN

CAS: 928672-86-0

Formula: C₄₈H₅₂F₂O₁₁S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 907.0467

Ref: IN-DA00IHD7

Canagliflozin Hemihydrate

CAS: 928672-86-0

Canagliflozin Hemihydrate

Purity: 98%

Molecular weight: 907.05g/mol

Ref: 54-PC109209

Canagliflozin hemihydrate

CAS: 928672-86-0

Canagliflozin hemihydrate

Purity: ≥98%

Molecular weight: 907.05g/mol

Ref: 54-BUP11682

Canagliflozin hemihydrate

CAS: 928672-86-0

Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.

Formula: C₄₈H₅₂F₂O₁₁S₂

Purity: 99.42% - 99.96%

Color and Shape: Solid

Molecular weight: 907.05

Ref: TM-T1782L

Canagliflozin hemihydrate

CAS: 928672-86-0

Canagliflozin is an oral diabetes drug that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking reabsorption of glucose in the kidney, thereby lowering blood sugar levels. Canagliflozin has been shown to be a potent inhibitor of insulin resistance and has been used clinically in combination with metformin hydrochloride. The chemical stability of canagliflozin is dependent on its particle size, which can range from 10 micrometres to 100 micrometres. A number of analytical methods have been developed for canagliflozin, including high performance liquid chromatography with ultraviolet detection, gas chromatography with mass spectrometry detection, and dihedral angle analysis. Canagliflozin is an example of a polymorphic compound: it exists as two enantiomers due to chiral symmetry.

Formula: (C₂₄H₂₅FO₅S)₂•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 907.05 g/mol

Ref: 3D-FC103621

Canagliflozin Hemihydrate

CAS: 928672-86-0

Formula: C₂₄H₂₅FO₅S(H₂O)

Molecular weight: 444.5 : 1/2(18.0)

Ref: ST-EA-CP-C7045