CAS 929016-96-6

Pracinostat

Description:

Pracinostat is a small molecule classified as a histone deacetylase (HDAC) inhibitor, primarily investigated for its potential therapeutic applications in cancer treatment. It is known to modulate gene expression by altering the acetylation status of histones, which can lead to the reactivation of tumor suppressor genes and the induction of apoptosis in cancer cells. Pracinostat has shown promise in preclinical studies and clinical trials, particularly in combination with other therapies for hematological malignancies and solid tumors. Its chemical structure features a specific arrangement of functional groups that contribute to its biological activity. The substance is typically administered orally and has been evaluated for its safety and efficacy in various cancer types. As with many HDAC inhibitors, potential side effects may include gastrointestinal disturbances, fatigue, and hematological changes. Ongoing research continues to explore its full therapeutic potential and mechanisms of action in oncology.

Formula: C₂₀H₃₀N₄O₂

InChI: InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+

InChI key: InChIKey=JHDKZFFAIZKUCU-ZRDIBKRKSA-N

SMILES: C(CN(CC)CC)N1C=2C(N=C1CCCC)=CC(/C=C/C(NO)=O)=CC2

Synonyms:

• (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide
• (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxyacrylamide
• (E)-3-[2-Butyl-1-(2-diethylaminoethyl)-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide
• 2-Propenamide, 3-[2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-, (2E)-
• Sb 939
• Sb939
• Pracinostat

Pracinostat (SB939)

CAS: 929016-96-6

Formula: C₂₀H₃₀N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.4778

Ref: IN-DA00GTBP

Pracinostat

CAS: 929016-96-6

Pracinostat

Purity: ≥98%

Molecular weight: 358.48g/mol

Ref: 54-BUP07163

Pracinostat

CAS: 929016-96-6

Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral

Formula: C₂₀H₃₀N₄O₂

Purity: 99.15% - 99.67%

Color and Shape: Solid

Molecular weight: 358.48

Ref: TM-T1890

Pracinostat

CAS: 929016-96-6

Purity: 98%

Molecular weight: 358.486

Ref: 10-F979122

SB 939

CAS: 929016-96-6

Formula: C₂₀H₃₀N₄O₂

Purity: 95.0%

Molecular weight: 358.486

Ref: 10-F468349

Pracinostat

Controlled Product

CAS: 929016-96-6

Formula: C₂₀H₃₀N₄O₂

Color and Shape: Neat

Molecular weight: 358.478

Ref: TR-P699100

Pracinostat

CAS: 929016-96-6

Inhibitor of histone deacetylase

Formula: C₂₀H₃₀N₄O₂

Purity: Min. 95%

Color and Shape: White To Pink To Yellow Solid

Molecular weight: 358.48 g/mol

Ref: 3D-FP43359