CAS 93076-89-2

diacylglycerol kinase inhibitor I

Description:

Diacylglycerol kinase inhibitor I, with the CAS number 93076-89-2, is a chemical compound that serves as an inhibitor of diacylglycerol kinase (DGK), an enzyme involved in lipid signaling pathways. This compound is primarily used in biochemical research to study the role of diacylglycerol in cellular processes, including signal transduction and membrane dynamics. Inhibition of DGK can lead to increased levels of diacylglycerol, which is a crucial second messenger in various signaling pathways. The substance is typically characterized by its ability to selectively inhibit DGK activity, thereby influencing cellular responses related to growth, differentiation, and apoptosis. Its chemical structure includes functional groups that facilitate its interaction with the enzyme's active site. As a research tool, diacylglycerol kinase inhibitor I is valuable for elucidating the physiological roles of diacylglycerol and for exploring potential therapeutic applications in diseases where lipid signaling is disrupted. Safety and handling precautions should be observed, as with all chemical substances used in laboratory settings.

Formula: C₂₇H₂₆FN₃OS

InChI: InChI=1/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10,17-18H,11-16H2,1H3

SMILES: Cc1c(CCN2CCC(=C(c3ccccc3)c3ccc(cc3)F)CC2)c(=O)n2ccsc2n1

Synonyms:

• R 59022
• 6-(2-(4-((4-Fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo(3,2-a)pyrimidine-5-one
• R 59-022
• R59022
• 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-((4-fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-
• 6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one

Diacylglycerol Kinase Inhibitor I

CAS: 93076-89-2

Formula: C₂₇H₂₆FN₃OS

Purity: 97%

Color and Shape: Solid

Molecular weight: 459.5782

Ref: IN-DA00GRTS

Diacylglycerol Kinase Inhibitor I

CAS: 93076-89-2

Formula: C₂₇H₂₆FN₃OS

Molecular weight: 459.58

Ref: 7W-GL1895

R 59-022

CAS: 93076-89-2

R 59-022

Purity: ≥98%

Molecular weight: 459.58g/mol

Ref: 54-BUP01642

R 59-022

CAS: 93076-89-2

R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.

Formula: C₂₇H₂₆FN₃OS

Purity: 98.55%

Color and Shape: Solid

Molecular weight: 459.58

Ref: TM-T16709

R-59-022-d5 (Mono-defluoro Ritanserin-d5)

Controlled Product

CAS: 93076-89-2

Formula: C₂₇D₅H₂₁FN₃OS

Color and Shape: Neat

Molecular weight: 464.609

Ref: TR-R020002

R-59-022 (Diacylglycerol Kinase Inhibitor I)

Controlled Product

CAS: 93076-89-2

Formula: C₂₇H₂₆FN₃OS

Color and Shape: Neat

Molecular weight: 459.578

Ref: TR-R020000

Diacylglycerol Kinase Inhibitor I

CAS: 93076-89-2

Diacylglycerol Kinase Inhibitor I is a drug that inhibits diacylglycerol kinase, a key enzyme in the production of prostaglandins. This drug is made from polymers and has a hydrophobic, inorganic matrix. It can be used for the treatment of periodontal disease and will be delivered to the periodontium through an implantable device. The matrix will degrade over time and the growth factor will stimulate new bone formation. The particle size of Diacylglycerol Kinase Inhibitor I is less than 2mm in diameter and it is coated with coatings such as titanium oxide, silicon dioxide, or hydroxyapatite.

Formula: C₂₇H₂₆FN₃OS

Purity: Min. 95%

Molecular weight: 459.58 g/mol

Ref: 3D-TDA07689