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CAS 93076-89-2

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diacylglycerol kinase inhibitor I

Description:
Diacylglycerol kinase inhibitor I, with the CAS number 93076-89-2, is a chemical compound that serves as an inhibitor of diacylglycerol kinase (DGK), an enzyme involved in lipid signaling pathways. This compound is primarily used in biochemical research to study the role of diacylglycerol in cellular processes, including signal transduction and membrane dynamics. Inhibition of DGK can lead to increased levels of diacylglycerol, which is a crucial second messenger in various signaling pathways. The substance is typically characterized by its ability to selectively inhibit DGK activity, thereby influencing cellular responses related to growth, differentiation, and apoptosis. Its chemical structure includes functional groups that facilitate its interaction with the enzyme's active site. As a research tool, diacylglycerol kinase inhibitor I is valuable for elucidating the physiological roles of diacylglycerol and for exploring potential therapeutic applications in diseases where lipid signaling is disrupted. Safety and handling precautions should be observed, as with all chemical substances used in laboratory settings.
Formula:C27H26FN3OS
InChI:InChI=1/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10,17-18H,11-16H2,1H3
InChI key:MFVJXLPANKSLLD-UHFFFAOYSA-N
SMILES:Cc1c(CCN2CCC(=C(c3ccccc3)c3ccc(cc3)F)CC2)c(=O)n2ccsc2n1
Synonyms:
  • R 59022
  • 6-(2-(4-((4-Fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo(3,2-a)pyrimidine-5-one
  • R 59-022
  • R59022
  • 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-((4-fluorophenyl)phenylmethylene)-1-piperidinyl)ethyl)-7-methyl-
  • 6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one
Found 8 products.