CAS 93261-39-3

Formula: C17H10N2O6

InChI: InChI=1S/C17H10N2O6/c20-17(12-8-13(18(21)22)10-14(9-12)19(23)24)25-16-7-3-5-11-4-1-2-6-15(11)16/h1-10H

InChI key: WYKPSINHJUWDHK-UHFFFAOYSA-N

SMILES: C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC(=CC(=C3)[N+](=O)[O-])[N+](=O)[O-]

1-Naphthyl 3,5-dinitrobenzoate

CAS: 93261-39-3

1-Naphthyl 3,5-dinitrobenzoate

Formula: C₁₇H₁₀N₂O₆

Purity: ≥95%

Molecular weight: 338.27

Ref: 54-BUP02689

1-Naphthyl 3,5-dinitrobenzoate

CAS: 93261-39-3

1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.

Formula: C₁₇H₁₀N₂O₆

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 338.2711

Ref: TM-T21838

1-Naphthyl 3,5-dinitrobenzoate

CAS: 93261-39-3

Formula: C₁₇H₁₀N₂O₆

Molecular weight: 338.2711

Ref: IN-DA01EPKU

JMC-4

CAS: 93261-39-3

JMC-4 is a novel anti-inflammatory agent that belongs to the class of lipoxygenase inhibitors. It is an optimized conformation of JMC-1 and has shown covalent binding to lipoxygenase with high affinity. JMC-4 has been shown to inhibit lipoxygenase activity in a blood assay and in fruit extracts. The molecular electrostatic potential of JMC-4 was calculated using QM/MM calculations and its active conformation was determined by X-ray crystallography. The conformational change in the active conformation of JMC-4 is due to the formation of hydrogen bonds with neighboring molecules, leading to a more hydrophobic environment for the active site.

Formula: C₁₇H₁₀N₂O₆

Purity: Min. 95%

Molecular weight: 338.27 g/mol

Ref: 3D-TDA26139