CAS 933-88-0
:2-Methylbenzoyl chloride
Description:
2-Methylbenzoyl chloride, with the CAS number 933-88-0, is an aromatic acyl chloride characterized by its structure, which features a benzene ring substituted with a methyl group and a carbonyl chloride functional group. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity. It is soluble in organic solvents such as dichloromethane and ether but is not soluble in water due to its hydrophobic nature. 2-Methylbenzoyl chloride is known for its role as an acylating agent in organic synthesis, particularly in the preparation of various derivatives and intermediates in pharmaceuticals and agrochemicals. It reacts readily with nucleophiles, including alcohols and amines, to form esters and amides, respectively. Due to its reactive nature, it must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.
Formula:C8H7ClO
InChI:InChI=1S/C8H7ClO/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3
InChI key:InChIKey=GPZXFICWCMCQPF-UHFFFAOYSA-N
SMILES:C(Cl)(=O)C1=C(C)C=CC=C1
Synonyms:- 2-Methyl Benzoyl Chloride
- 2-Methylbenzoic acid chloride
- 2-Methylbenzoyl Chloride
- 2-Toluoyl chloride
- Benzoyl chloride, 2-methyl-
- Chlorure de o-toluoyle
- Cloruro De O-Toluoilo
- Methylbenzoyl Chloride
- O-Methyl-Benzoyl-Chloride
- O-Methylbenzoyl Chloride
- Ortho-Toluoyl Chloride
- Toluoyl Chloride, Ortho
- Toluoylchloride
- o-Toluic acid chloride
- o-Toluoylchlorid
- o-Toluyl chloride
- See more synonyms
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Found 10 products.
o-Toluoyl chloride, 98+%
CAS:o-Toluoyl chloride is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference haFormula:C8H7ClOPurity:98+%Color and Shape:Clear colorless to pale yellow, LiquidMolecular weight:154.59o-Toluoyl Chloride
CAS:Formula:C8H7ClOPurity:>98.0%(GC)(T)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:154.592-Methylbenzoyl chloride
CAS:2-Methylbenzoyl chlorideFormula:C8H7ClOPurity:95%Color and Shape:Colourless LiquidMolecular weight:154.593572-Methylbenzoyl chloride
CAS:2-Methylbenzoyl chlorideFormula:C8H7ClOPurity:98%Molecular weight:154.59O-Toluoyl Chloride
CAS:Controlled ProductApplications O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.
References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);Formula:C8H7ClOColor and Shape:NeatMolecular weight:154.59O-Toluoyl Chloride-13C6
CAS:Controlled ProductFormula:C6C2H7ClOColor and Shape:NeatMolecular weight:160.549o-Toluoyl chloride
CAS:o-Toluoyl chloride is an antidiabetic agent that inhibits the production of glucose by inhibiting the enzyme glucosidase. It also prevents the absorption of glucose in the small intestine and blocks pancreatic alpha-amylase, which is an enzyme that breaks down starch into maltose. The chemical reaction mechanism for o-toluoyl chloride is a substitution reaction with a hydroxyl group and a benzoate, forming a cation channel. This leads to an increase in the intracellular concentration of cations, which can contribute to inflammatory bowel disease. The biological studies have shown that light emission is generated when o-toluoyl chloride reacts with 2-methyl-4-nitrobenzoic acid. This process has been used as a method for detecting this compound.Formula:C8H7ClOPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:154.59 g/mol
