CAS 934294-22-1

2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-4,5,6,7-d₄

Description:

The chemical substance known as 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-4,5,6,7-d4 is a deuterated compound, indicated by the presence of deuterium (d) in its structure. This compound features a benzimidazole core, which is a bicyclic structure containing both benzene and imidazole rings, contributing to its potential biological activity. The presence of a sulfinyl group suggests that it may exhibit unique reactivity or interactions due to the sulfur atom's oxidation state. The trifluoroethoxy group enhances lipophilicity and may influence the compound's pharmacokinetic properties. Additionally, the methyl and pyridine substituents can affect the compound's electronic properties and steric hindrance, potentially impacting its binding affinity to biological targets. Overall, this compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its complex structure and the presence of multiple functional groups that can interact with biological systems.

Formula: C₁₆H₁₀D₄F₃N₃O₂S

InChI: InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/i2D,3D,4D,5D

InChI key: InChIKey=MJIHNNLFOKEZEW-QFFDRWTDSA-N

SMILES: S(CC1=C(C)C(OCC(F)(F)F)=CC=N1)(=O)C=2NC=3C(N2)=C(C(=C(C3[2H])[2H])[2H])[2H]

Synonyms:

• 1H-Benzimidazole-4,5,6,7-d4, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
• 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-4,5,6,7-d4
• A-65006-d4
• AG-1749-d4
• LANSOPRAZOLE-D4
• Agopton-d4
• Prevacid-d4
• Limpidex-d4
• Lansox-d4
• Lanzor-d4
• 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole-d4

Lansoprazole-d4

CAS: 934294-22-1

Formula: C₁₆H₁₀D₄F₃N₃O₂S

Color and Shape: Light Yellow Solid

Molecular weight: 373.39

Ref: 4Z-L-034

Lansoprazole-d4 (benzimidazole-4,5,6,7-d4)

CAS: 934294-22-1

Purity: 98 atom % D

Color and Shape: Off-White To Yellow Solid

Molecular weight: 373.39

Ref: 3U-D6096

Lansoprazole-d4

CAS: 934294-22-1

Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.

Formula: C₁₆H₁₄F₃N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 373.39

Ref: TM-T11816

Lansoprazole-d4

Controlled Product

CAS: 934294-22-1

Formula: C₁₆₂H₄H₁₀F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 373.39

Ref: TR-L175002

(R)-Lansoprazole-d4

Controlled Product

CAS: 138530-94-6, 934294-22-1

Applications The labelled R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.
References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),

Formula: C₁₆H₁₀D₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 373.39

Ref: TR-L175012