CAS 934343-74-5
:HSP-990
Description:
HSP-990, with the CAS number 934343-74-5, is a small molecule inhibitor that primarily targets heat shock protein 90 (Hsp90), a chaperone protein involved in the proper folding and stabilization of various client proteins, many of which are implicated in cancer and other diseases. As a potent inhibitor, HSP-990 disrupts the function of Hsp90, leading to the degradation of its client proteins, which can result in anti-tumor effects. The compound has been studied for its potential therapeutic applications in oncology, particularly in the treatment of various cancers where Hsp90 is overexpressed or plays a critical role in tumor growth and survival. HSP-990 exhibits favorable pharmacokinetic properties, including good oral bioavailability and a manageable safety profile in preclinical studies. Its mechanism of action and specificity make it a subject of interest in drug development, particularly in combination therapies aimed at enhancing the efficacy of existing cancer treatments. Further research is ongoing to fully elucidate its therapeutic potential and optimize its clinical application.
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Found 7 products.
NVP-HSP990
CAS:(R)-2-Amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-oneFormula:C20H18FN5O2Purity:98%Molecular weight:379.39(R)-2-Amino-7-(4-Fluoro-2-(6-Methoxypyridin-2-Yl)Phenyl)-4-Methyl-7,8-Dihydropyrido[4,3-d]Pyrimidin-5(6H)-One
CAS:(R)-2-Amino-7-(4-Fluoro-2-(6-Methoxypyridin-2-Yl)Phenyl)-4-Methyl-7,8-Dihydropyrido[4,3-d]Pyrimidin-5(6H)-OneFormula:C20H18FN5O2Purity:98%Molecular weight:379.39NVP-HSP990
CAS:NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).Formula:C20H18FN5O2Purity:98.03% - 99.32%Color and Shape:White SolidMolecular weight:379.39
