CAS: 935888-69-0 - Oprozomib

Formula: C₂₅H₃₂N₄O₇S

InChI: InChI=1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1

InChI key: InChIKey=SWZXEVABPLUDIO-WSZYKNRRSA-N

SMILES: O=C(NC(C(=O)NC(C(=O)NC(C(=O)C1(OC1)C)CC=2C=CC=CC2)COC)COC)C=3SC(=NC3)C

Synonyms:

• ONX 0912
• Oprozomib
• O-Methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide
• PR 047
• L-Serinamide, O-methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-

ONX-0912

CAS: 935888-69-0

• Formula: C₂₅H₃₂N₄O₇S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 532.6092

Oprozomib

CAS: 935888-69-0

• Formula: C₁₅H₃₂N₄O₇S
• Color and Shape: White To Off-White Solid
• Molecular weight: 532.62

Oprozomib-d6

CAS: 935888-69-0

• Formula: C₁₅H₂₆N₄O₇SD₆
• Molecular weight: 538.66

Oprozomib [ONX 0912]

CAS: 935888-69-0

Oprozomib

CAS: 935888-69-0

Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 …

• Formula: C₂₅H₃₂N₄O₇S
• Purity: 98% - 99.87%
• Color and Shape: Solid
• Molecular weight: 532.61

Oprozomib

CAS: 935888-69-0

Applications Oprozomib is the second class of proteasome inhibitors with higher specificities and reduced toxicities, …

• Formula: C₂₅H₃₂N₄O₇S
• Color and Shape: Neat
• Molecular weight: 532.61

Oprozomib

CAS: 935888-69-0

Proteosome inhibitor; pro-apoptotic; has anti-myeloma activity

• Formula: C₂₅H₃₂N₄O₇S
• Purity: Min. 95%
• Color and Shape: White To Off-White Solid
• Molecular weight: 532.61 g/mol