CAS: 936091-26-8 - n-(1,1-dimethylethyl)-3-((5-methyl-2-((4-(2-(1-pyrrolidinyl)ethoxy)phenyl)amino)-4-pyrimidinyl)amino)benzenesulfonamide

Formula: C₂₇H₃₆N₆O₃S

InChI: InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)

InChI key: InChIKey=JOOXLOJCABQBSG-UHFFFAOYSA-N

SMILES: O=S(=O)(NC(C)(C)C)C=1C=CC=C(C1)NC2=NC(=NC=C2C)NC3=CC=C(OCCN4CCCC4)C=C3

Synonyms:

• Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]-
• Fedratinib
• Inrebic
• Sar 302503
• TG101348 HCl
• Tg 101348
• Tg 10138
• Tg101348

Fedratinib (SAR302503, TG101348)

CAS: 936091-26-8

• Formula: C₂₇H₃₆N₆O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 524.6781

Fedratinib

CAS: 936091-26-8

• Formula: C₂₇H₃₆N₆O₃S
• Molecular weight: 524.68

Fedratinib

CAS: 936091-26-8

Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less …

• Formula: C₂₇H₃₆N₆O₃S
• Purity: 99.96%
• Color and Shape: Solid
• Molecular weight: 524.68

TG101348

CAS: 936091-26-8

TG101348

CAS: 936091-26-8

Applications TG101348 is a selective inhibitor of JAK2 tyrosine kinase. Potent JAK2 inhibitor. References Rosenthal, …

• Formula: C₂₇H₃₆N₆O₃S
• Color and Shape: White To Off-White
• Molecular weight: 524.68

Fedratinib

CAS: 936091-26-8

JAK2 inhibitor with potential antineoplastic activity

• Formula: C₂₇H₃₆N₆O₃S
• Purity: Min. 95%
• Molecular weight: 524.68 g/mol