CAS 936250-22-5

(2-Aminopyrimidin-5-yl)boronic acid

Description:

(2-Aminopyrimidin-5-yl)boronic acid is an organic compound characterized by the presence of both a pyrimidine ring and a boronic acid functional group. The pyrimidine moiety contributes to its aromatic properties, while the boronic acid group is known for its ability to form reversible covalent bonds with diols, making it valuable in various chemical reactions, including Suzuki coupling. This compound typically exhibits moderate solubility in polar solvents, such as water and alcohols, due to the presence of the amino and boronic acid groups, which can engage in hydrogen bonding. Its structure allows for potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Additionally, (2-Aminopyrimidin-5-yl)boronic acid may serve as a building block in organic synthesis, facilitating the construction of more complex molecular architectures. As with many boronic acids, it is important to handle this compound with care, as it can be sensitive to moisture and air, which may affect its stability and reactivity.

Formula: C₄H₆BN₃O₂

InChI: InChI=1S/C4H6BN3O2/c6-4-7-1-3(2-8-4)5(9)10/h1-2,9-10H,(H2,6,7,8)

InChI key: InChIKey=CGHYQZASLKERLV-UHFFFAOYSA-N

SMILES: B(O)(O)C=1C=NC(N)=NC1

Synonyms:

• (2-Aminopyrimidin-5-yl)boronic acid
• 2-Amino-pyrimidine-5-boronic acid
• 2-Aminopyrimidine-5-boronic acid
• 2-Aminopyrimidine-5-boronicacid
• B-(2-Amino-5-pyrimidinyl)boronic acid
• boronic acid, B-(2-amino-5-pyrimidinyl)-

2-Aminopyrimidine-5-boronic Acid (contains varying amounts of Anhydride)

CAS: 936250-22-5

Formula: C₄H₆BN₃O₂

Purity: 98.0 to 115.0 %

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 138.92

Ref: 3B-A2900

2-Amino-pyrimidine-5-boronic acid

CAS: 936250-22-5

Formula: C₄H₆BN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 138.9203

Ref: IN-DA00GRM5

2-Aminopyrimidine-5-boronic acid

CAS: 936250-22-5

2-Aminopyrimidine-5-boronic acid

Purity: 98%

Color and Shape: Solid

Molecular weight: 138.92g/mol

Ref: 54-OR16625

(2-Aminopyrimidin-5-yl)boronic acid

CAS: 936250-22-5

Formula: C₄H₆BN₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 138.92

Ref: 10-F216344

2-Aminopyrimidine-5-boronic acid

Controlled Product

CAS: 936250-22-5

Stability Hygroscopic
Applications 2-Aminopyrimidine-5-boronic acid

Formula: C₄H₆BN₃O₂

Color and Shape: Neat

Molecular weight: 138.92

Ref: TR-A629258

2-Aminopyrimidine-5-boronic acid

CAS: 936250-22-5

2-Aminopyrimidine-5-boronic acid is a synthetic compound that has been shown to inhibit the activity of cellulase enzymes in vitro. It also has neuroprotective effects and potent inhibition against cancer cells. 2-Aminopyrimidine-5-boronic acid's mechanism of action is reversible covalent, meaning that it reacts with DNA by forming an N2-(2'-aminopyrimidine) adduct with guanine at position 6 in the purine ring. This reaction inhibits DNA synthesis, leading to cell death. 2-Aminopyrimidine-5-boronic acid is not currently being used as a cancer therapy, but it is being researched for its potential use in cancer treatments.

Formula: C₄H₆BN₃O₂

Purity: Min. 95%

Molecular weight: 138.92 g/mol

Ref: 3D-NA57424