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CAS 937263-43-9
:N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine
Description:
N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine, with CAS number 937263-43-9, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple heterocyclic rings. This compound features a quinazoline backbone, which is known for its biological activity, particularly in medicinal chemistry. The presence of oxazole and triazole moieties suggests potential interactions with biological targets, making it of interest in drug discovery and development. Its structure indicates that it may exhibit properties such as solubility in organic solvents and potential bioactivity, possibly as an inhibitor or modulator of specific enzymes or receptors. The compound's intricate arrangement of functional groups may also influence its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME). Overall, this compound represents a class of molecules that could be explored for therapeutic applications, particularly in oncology or infectious diseases, although specific biological activities would require empirical investigation.
Formula:C26H24N8O2
InChI:InChI=1S/C26H24N8O2/c1-16-10-17(5-7-22(16)36-19-8-9-34-23(12-19)28-15-30-34)31-24-20-11-18(4-6-21(20)27-14-29-24)32-25-33-26(2,3)13-35-25/h4-12,14-15H,13H2,1-3H3,(H,32,33)(H,27,29,31)
InChI key:InChIKey=SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES:N(C=1C2=C(C=CC(NC3=NC(C)(C)CO3)=C2)N=CN1)C4=CC(C)=C(OC5=CC=6N(C=C5)N=CN6)C=C4
Synonyms:- ARRY 380
- Tucatinib
- N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine
- 4,6-QuinazolinediaMine, N6-(4,5-dihydro-4,4-diMethyl-2-oxazolyl)-N4-[3-Methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-
- 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-
- ONT 380
- Tucatinib
- Irbinitinib
- 5-dihydrooxazol-2-yl)quinazoline-4
- 5-dihydrooxazol-2-yl)-N4-(3-Methyl-4-(thiazol-2-ylMethoxy)phenyl)quinazoline-4
- 5-a]pyridin-7-yloxy)-3-Methylphenyl)-N6-(4
- (R)-N6-(4-Methyl-4
- N4-(4-([1
- 6-diaMine
- 4-diMethyl-4
- See more synonyms
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Tucatinib
CAS:N4-(4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamineFormula:C26H24N8O2Purity:98%Molecular weight:480.52Tucatinib
CAS:Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formula:C26H24N8O2Purity:99.05% - 99.96%Color and Shape:SolidMolecular weight:480.52Ref: TM-T2364
2mg34.00€5mg50.00€1mL*10mM (DMSO)50.00€10mg74.00€25mg117.00€50mg177.00€100mg333.00€500mg782.00€1g1,071.00€Tucatinib
CAS:Tucatinib is a small molecule, tyrosine kinase inhibitor, which is a synthetic, targeted therapeutic agent with a specific mode of action. It specifically inhibits the kinase activity of the human epidermal growth factor receptor 2 (HER2), a member of the epidermal growth factor receptor (EGFR) family. HER2 is overexpressed in a significant subset of breast cancers, leading to aggressive tumor characteristics and poor prognosis.Formula:C26H24N8O2Purity:Min. 95%Molecular weight:480.52 g/mol
