![(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F29681-2e-3-3-4-fluorophenyl-1-1-methylethyl-1h-indol-2-yl-2-propenal.webp&w=3840&q=75)
CAS 93957-50-7
:(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
Description:
The chemical substance known as (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal, with CAS number 93957-50-7, is characterized by its complex structure, which includes an indole moiety and a propenal functional group. This compound features a fluorophenyl group, which contributes to its potential biological activity and lipophilicity. The presence of the isopropyl group on the indole ring enhances its steric properties, possibly influencing its interactions with biological targets. The propenal part of the molecule indicates that it may participate in various chemical reactions, including Michael additions or conjugate additions, due to the presence of the α,β-unsaturated carbonyl system. This compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. Its specific characteristics, such as solubility, stability, and reactivity, would depend on the surrounding conditions and the presence of other functional groups in a given environment.
Formula:C20H18FNO
InChI:InChI=1S/C20H18FNO/c1-14(2)22-18-7-4-3-6-17(18)20(19(22)8-5-13-23)15-9-11-16(21)12-10-15/h3-14H,1-2H3/b8-5+
InChI key:InChIKey=DVWHSTKQJBIYCK-VMPITWQZSA-N
SMILES:C(=C/C=O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3
Synonyms:- (2E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-2-Propenal
- (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
- (E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-Methylethyl)-1H-Indol-2''-Yl]-2-Propnal
- (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
- (E)-3-[3-(4-fluorophenyl)-1-(1-methylethyl)-2-indolyl]propenal
- 2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
- 2-Propenal,3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (E)-
- Fluvastatin intermediate
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Found 8 products.
2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
CAS:Formula:C20H18FNOPurity:98%Color and Shape:SolidMolecular weight:307.3614(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehydePurity:98%Molecular weight:307.37g/mol(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein
CAS:Formula:C20H18FNOPurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:307.37(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:307.3680114746094(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal
CAS:<p>(E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal is an amoebicidal agent that belongs to the class of indole derivatives. It has been shown to inhibit tumor growth in animal models, and thus may be a potential anti-cancer drug. The activity index of (E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal was significantly lower than those of fenoldopam, a well known antihypertensive agent, for the treatment of liver cancer. The compound also inhibits the growth of bacteria by inhibiting protein synthesis in organisms such as amoeba.</p>Formula:C20H18FNOPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:307.36 g/mol(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7
CAS:Controlled Product<p>Applications (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7 an isotope labelled reactant used in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor.<br>References Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)<br></p>Formula:C20D7H11FNOColor and Shape:NeatMolecular weight:314.405(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:Controlled ProductFormula:C20H18FNOColor and Shape:NeatMolecular weight:307.36
![2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003C0F.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FF0819.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]prop-2-enal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0676.14-0025.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF036562.jpg&w=3840&q=75)
![(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFF37514.jpg&w=3840&q=75)
