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CAS 93957-55-2

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Fluvastatin sodium

Description:
Fluvastatin sodium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. It functions as an HMG-CoA reductase inhibitor, which plays a crucial role in cholesterol biosynthesis. The compound is characterized by its ability to lower low-density lipoprotein (LDL) cholesterol levels while modestly increasing high-density lipoprotein (HDL) cholesterol. Fluvastatin sodium is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability is affected by first-pass metabolism in the liver. The drug is generally well-tolerated, but potential side effects may include muscle pain, liver enzyme abnormalities, and gastrointestinal disturbances. It is contraindicated in patients with active liver disease or those who are pregnant or breastfeeding. Fluvastatin sodium is often prescribed in conjunction with dietary modifications and lifestyle changes to enhance its efficacy in cholesterol management. Regular monitoring of lipid levels and liver function tests is recommended during treatment.
Formula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
InChI key:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Synonyms:
  • (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
  • Almastatin
  • Canef
  • Cranoc
  • Fluindostatin
  • Fluvastatin Sodium Salt
  • Fractal
  • See more synonyms
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Found 19 products.
  • Fluvastatin Sodium Salt

    CAS:
    Formula:C24H25FNNaO4
    Purity:>98.0%(HPLC)(N)
    Color and Shape:Light orange to Yellow to Green powder to crystal
    Molecular weight:433.46

    Ref: 3B-F0820

    1g
    75.00€
    5g
    256.00€
  • Fluvastatin Sodium

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR0676.00

    10mg
    302.00€
  • Fluvastatin sodium

    CAS:
    Fluvastatin sodium
    Formula:C24H25NNaO4
    Purity:97.4%
    Color and Shape:Light Yellow. To. Orange
    Molecular weight:414.16813

    Ref: 47-1163

    100mg
    242.00€
  • FLUVASTATIN SODIUM CRS

    CAS:
    <p>FLUVASTATIN SODIUM CRS</p>
    Formula:C24H25FNNaO4
    Color and Shape:White. Orange. Light Yellow. Powder.
    Molecular weight:433.4478

    Ref: 41-Y0001090

    110mg
    115.00€
  • FLUVASTATIN FOR SYSTEM SUITABILITY CRS

    CAS:
    <p>FLUVASTATIN FOR SYSTEM SUITABILITY CRS</p>
    Formula:C24H25FNNaO4
    Molecular weight:433.4478

    Ref: 41-Y0001082

    0.5mg
    115.00€
  • sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate

    CAS:
    Formula:C24H25FNNaO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.4478

    Ref: IN-DA003QMD

    1g
    93.00€
    50mg
    43.00€
    100mg
    61.00€
    250mg
    64.00€
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>
    Formula:C24H25FNNaO4
    Purity:98.54% - 99.56%
    Color and Shape:Light Yellow Solid Powder
    Molecular weight:433.45
  • Fluvastatin Sodium Salt

    CAS:
    Formula:C24H25FNO4·Na
    Color and Shape:Yellow Solid
    Molecular weight:410.47 22.99

    Ref: 4Z-F-101

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium</p>
    Purity:≥98%
    Molecular weight:433.45g/mol

    Ref: 54-BUP13738

    10mg
    53.00€
    25mg
    70.00€
    50mg
    96.00€
    100mg
    135.00€
    200mg
    184.00€
    500mg
    269.00€
  • Fluvastatin-d6 Sodium Salt

    CAS:
    Formula:C24H19D6FNO4·Na
    Color and Shape:Off-White Solid
    Molecular weight:416.50 22.99

    Ref: 4Z-F-102

    5mg
    To inquire
    10mg
    1,942.00€
    25mg
    3,580.00€
    50mg
    5,764.00€
    100mg
    To inquire
  • Fluvastatin sodium salt

    CAS:
    Formula:C24H25FNO4·Na·xH2O
    Purity:98.0 - 102.0 % (anhydrous basis)
    Color and Shape:Off-white to pale yellow or light yellow-orange powder
    Molecular weight:433.45 (anhydrous)

    Ref: 7W-GP9431

    1g
    79.00€
  • Fluvastatin sodium

    Controlled Product
    CAS:
    Formula:C24H25FNO4·Na
    Color and Shape:Neat
    Molecular weight:433.45

    Ref: 04-C13871000

    100mg
    100.00€
  • Fluvastatin Sodium

    CAS:
    Color and Shape:Light Yellow To Orange

    Ref: 86-MM0676.00

    250mg
    3,230.00€
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium</p>
    Purity:98%
    Molecular weight:433.45g/mol

    Ref: 54-BISN0143

    1g
    118.00€
    5g
    328.00€
    25g
    1,123.00€
    100mg
    32.00€
    250mg
    55.00€
  • Fluvastatin-d6 Sodium

    Controlled Product
    CAS:
    <p>Applications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);<br></p>
    Formula:C24H19D6FNNaO4
    Color and Shape:Neat
    Molecular weight:439.48

    Ref: TR-F601253

    1mg
    360.00€
    10mg
    2,461.00€
  • Fluvastatin Sodium Salt(Relative Stereochemistry)

    CAS:
    <p>Stability Hygroscopic<br>Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);<br></p>
    Formula:C24H25FNO4·Na
    Color and Shape:Neat
    Molecular weight:433.45

    Ref: TR-F601250

    25mg
    100.00€
    250mg
    197.00€
    500mg
    235.00€
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.</p>
    Formula:C24H25FNNaO4
    Purity:Min. 98%
    Color and Shape:Off-White Powder
    Molecular weight:433.45 g/mol

    Ref: 3D-FF23520

    2g
    203.00€
    5g
    305.00€
    10g
    477.00€
    25g
    804.00€
    50g
    1,213.00€
  • Fluvastatin sodium salt - Bio-X ™

    CAS:
    <p>Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.</p>
    Formula:C24H25FNNaO4
    Purity:Min. 98%
    Molecular weight:433.45 g/mol

    Ref: 3D-BF164477

    10mg
    135.00€
  • Fluvastatin Sodium

    CAS:
    <p>Cardiovascular drugs, not elsewhere specified or included</p>
    Formula:C24H25FNNaO4
    Color and Shape:White Yellow Powder
    Molecular weight:433.16653

    Ref: 45-1285931

    2x350mg_old
    Discontinued
    Discontinued product