CAS 93957-55-2
:Fluvastatin sodium
Description:
Fluvastatin sodium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. It functions as an HMG-CoA reductase inhibitor, which plays a crucial role in cholesterol biosynthesis. The compound is characterized by its ability to lower low-density lipoprotein (LDL) cholesterol levels while modestly increasing high-density lipoprotein (HDL) cholesterol. Fluvastatin sodium is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability is affected by first-pass metabolism in the liver. The drug is generally well-tolerated, but potential side effects may include muscle pain, liver enzyme abnormalities, and gastrointestinal disturbances. It is contraindicated in patients with active liver disease or those who are pregnant or breastfeeding. Fluvastatin sodium is often prescribed in conjunction with dietary modifications and lifestyle changes to enhance its efficacy in cholesterol management. Regular monitoring of lipid levels and liver function tests is recommended during treatment.
Formula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
InChI key:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Synonyms:- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
- Almastatin
- Canef
- Cranoc
- Fluindostatin
- Fluvastatin Sodium Salt
- Fractal
- Lescol
- Lescol XL
- Lochol
- Locol
- Sodium (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
- Vastin
- Xu 62-320
- sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
- See more synonyms
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Fluvastatin Sodium Salt
CAS:Formula:C24H25FNNaO4Purity:>98.0%(HPLC)(N)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:433.46(3S,5R)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid sodium salt
CAS:(3S,5R)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid sodium saltPurity:97%Color and Shape:SolidMolecular weight:433.17FLUVASTATIN FOR SYSTEM SUITABILITY CRS
CAS:FLUVASTATIN FOR SYSTEM SUITABILITY CRSFormula:C24H25FNNaO4Molecular weight:433.4478Fluvastatin sodium
CAS:Fluvastatin sodiumFormula:C24H25NNaO4Purity:97.4%Color and Shape:Light Yellow. To. OrangeMolecular weight:414.16813FLUVASTATIN SODIUM CRS
CAS:FLUVASTATIN SODIUM CRSFormula:C24H25FNNaO4Color and Shape:White. Orange. Light Yellow. Powder.Molecular weight:433.4478Fluvastatin Sodium
CAS:Cardiovascular drugs, not elsewhere specified or includedFormula:C24H25FNNaO4Color and Shape:White Yellow PowderMolecular weight:433.16653Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purity:98.54% - 99.56%Color and Shape:SolidMolecular weight:433.45Fluvastatin Sodium Salt
CAS:Formula:C24H25FNO4·NaColor and Shape:Yellow SolidMolecular weight:410.47 22.99Fluvastatin-d6 Sodium Salt
CAS:Formula:C24H19FNO4D6·NaColor and Shape:Off-White SolidMolecular weight:416.50 22.99Fluvastatin sodium salt
CAS:Formula:C24H25FNO4·Na·xH2OPurity:98.0 - 102.0 % (anhydrous basis)Color and Shape:Off-white to pale yellow or light yellow-orange powderMolecular weight:433.45 (anhydrous)Fluvastatin sodium
CAS:Controlled ProductFormula:C24H25FNO4·NaColor and Shape:NeatMolecular weight:433.45Fluvastatin sodium (Standard)
CAS:Fluvastatin sodium (Standard) is the standard substance of Fluvastatin sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.Formula:C24H25FNNaO4Molecular weight:433.45sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
CAS:Formula:C24H25FNNaO4Purity:98%Color and Shape:SolidMolecular weight:433.4478Fluvastatin Sodium
CAS:Formula:C24H25FNO4·NaColor and Shape:Light Yellow To OrangeMolecular weight:433.45Fluvastatin-d6 Sodium
CAS:Controlled ProductApplications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Formula:C24H19D6FNNaO4Color and Shape:NeatMolecular weight:439.48Fluvastatin Sodium Salt(Relative Stereochemistry)
CAS:Stability Hygroscopic
Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Formula:C24H25FNO4·NaColor and Shape:NeatMolecular weight:433.45rel-(3S,5R,E)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid, sodium salt
CAS:rel-(3S,5R,E)-7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid, sodium saltFormula:C24H25FNNaO4Purity:98%Molecular weight:433.45














