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CAS 93957-55-2

:

Fluvastatin sodium

Description:
Fluvastatin sodium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular disease. It functions as an HMG-CoA reductase inhibitor, which plays a crucial role in cholesterol biosynthesis. The compound is characterized by its ability to lower low-density lipoprotein (LDL) cholesterol levels while modestly increasing high-density lipoprotein (HDL) cholesterol. Fluvastatin sodium is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability is affected by first-pass metabolism in the liver. The drug is generally well-tolerated, but potential side effects may include muscle pain, liver enzyme abnormalities, and gastrointestinal disturbances. It is contraindicated in patients with active liver disease or those who are pregnant or breastfeeding. Fluvastatin sodium is often prescribed in conjunction with dietary modifications and lifestyle changes to enhance its efficacy in cholesterol management. Regular monitoring of lipid levels and liver function tests is recommended during treatment.
Formula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
InChI key:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Synonyms:
  • (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
  • 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
  • Almastatin
  • Canef
  • Cranoc
  • Fluindostatin
  • Fluvastatin Sodium Salt
  • Fractal
  • See more synonyms
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