CAS 94594-90-8

(2R)-Bornane-10,2-sultam

Description:

(2R)-Bornane-10,2-sultam, with the CAS number 94594-90-8, is a cyclic sulfonamide compound characterized by its unique bicyclic structure derived from bornane. This compound features a sulfonamide functional group, which contributes to its chemical reactivity and potential applications in various fields, including medicinal chemistry. The presence of the sultam ring indicates that it possesses both nitrogen and sulfur atoms within its structure, which can influence its solubility and interaction with biological systems. Typically, sultams exhibit interesting properties such as stability under certain conditions and the ability to participate in various chemical reactions, including nucleophilic substitutions. The stereochemistry denoted by (2R) indicates a specific spatial arrangement of atoms, which can affect the compound's biological activity and interactions. Overall, (2R)-Bornane-10,2-sultam is of interest for its potential applications in drug development and as a synthetic intermediate in organic chemistry.

Formula: C₁₀H₁₇NO₂S

InChI: InChI=1/C10H17NO2S/c1-9(2)7-3-4-10(9)6-14(12,13)11-8(10)5-7/h7-8,11H,3-6H2,1-2H3/t7-,8-,10+/m0/s1

Synonyms:

• [3aS-(3aalpha,6alpha,7abeta)]-Hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole 2,2-dioxide
• (1S)-(-)-2,10,Camphor sultam
• 8,8-Dimethyloctahydro-4,7-Methano-2,1-Benzothiazole 2,2-Dioxide
• (7aR)-8,8-dimethylhexahydro-3a,6-methano-2,1-benzothiazole 2,2-dioxide
• (3aS,6R,7aR)-8,8-dimethylhexahydro-3a,6-methano-2,1-benzothiazole 2,2-dioxide
• (6R)-8,8-dimethylhexahydro-3a,6-methano-2,1-benzisothiazole 2,2-dioxide
• (3aS,6S,7aS)-8,8-dimethylhexahydro-3a,6-methano-2,1-benzisothiazole 2,2-dioxide
• (-)-Camphorsultam
• (1S)-(-)-2,10-Camphorsultam
• (1S)-(-)-2,11-Camphorsultam

(-)-10,2-Camphorsultam

CAS: 94594-90-8

Formula: C₁₀H₁₇NO₂S

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 215.31

Ref: 3B-C1325

(1S,2R)-(-)-10,2-Camphorsultam, 99%

CAS: 94594-90-8

(1S,2R)-(-)-10,2-Camphorsultam is used in the asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl--methylcysteine. It is used as proton source in the synthesis of chiral ,-substituted -butyrolactones. It is also employed as a chiral probe for the optical resolution by HPLC and X-ray crystallographi

Formula: C₁₀H₁₇NO₂S

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 215.31

Ref: 02-A15897

(3aS,6R,7aR)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide

CAS: 94594-90-8

Formula: C₁₀H₁₇NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.3125

Ref: IN-DA003BJT

(1S,5R)-10,10-Dimethyl-3-Thia-4-Azatricyclo[5.2.1.0(1,5)]Decane 3,3-Dioxide

CAS: 94594-90-8

(1S,5R)-10,10-Dimethyl-3-Thia-4-Azatricyclo[5.2.1.0(1,5)]Decane 3,3-Dioxide

Purity: 97%

Molecular weight: 215.31g/mol

Ref: 54-OR1007931

(-)-10,2-Camphorsultam

CAS: 94594-90-8

Formula: C₁₀H₁₇NO₂S

Molecular weight: 215.32

Ref: 7W-GK5124

(1S)-(-)-2,10-Camphorsultam

CAS: 94594-90-8

Formula: C₁₀H₁₇NO₂S

Purity: 98%

Color and Shape: Crystalline

Molecular weight: 215.31

Ref: 10-F078916

(1S)-Camphorsultam

Controlled Product

CAS: 94594-90-8

Applications (1S)-Camphorsultam is used as a chiral auxiliary to control the stereochemistry in order to obtain the desired stereoselective product. It’s also a reagent used to make Camphorsultam conjugates, and used as a catalyst with the help of a lewis acid in organic reactions such as the Diels-​Alder reaction, and the Grignard reaction.
References Springthorpe, B., et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007); Inoue, M., et al.: Nat. Chem., 2, 280 (2010); Chapuis, C., et al.: Pol. J. Chem., 68, 2323-31 (1994); Merhcan, F.L., et al.: Tetrahedron: Asymmetry, 7, 667-70 (1996);

Formula: C₁₀H₁₇NO₂S

Color and Shape: Neat

Molecular weight: 215.13

Ref: TR-C175125