CAS 947692-16-2

Formula: C42H54N10O18S4

InChI: InChI=1S/C42H54N10O18S4/c1-17(2)65-41(59)69-19(5)67-37(57)25-21(11-61-7)13-71-34(48-25)28(46-31(53)26(50-63-9)23-15-73-39(43)44-23)33(55)49-40-45-24(16-74-40)27(51-64-10)32(54)47-29-35(56)52-30(22(12-62-8)14-72-36(29)52)38(58)68-20(6)70-42(60)66-18(3)4/h15-20,28-29,34,36,48H,11-14H2,1-10H3,(H2,43,44)(H,46,53)(H,47,54)(H,45,49,55)/b50-26-,51-27-/t19?,20?,28-,29-,34-,36-/m1/s1

InChI key: JVMMKKXXPLMCPK-XHLZYGRDSA-N

SMILES: CC(C)OC(=O)OC(C)OC(=O)C1=C(CS[C@@H](N1)[C@@H](C(=O)NC2=NC(=CS2)/C(=N/OC)/C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)COC)C(=O)OC(C)OC(=O)OC(C)C)NC(=O)/C(=N\OC)/C5=CSC(=N5)N)COC

Cefpodoxime Proxetil EP Impurity H

CAS: 947692-16-2

Formula: C₄₂H₅₄N₁₀O₁₈S₄

Molecular weight: 1115.19

Ref: 4Z-C-8513

Cefpodoxime Proxetil EP Impurity H

CAS: 947692-16-2

Formula: C₄₂H₅₄N₁₀O₁₈S₄

Molecular weight: 1115.19

Ref: ST-EA-CP-C156008

Cefpodoxime proxetil impurity H

CAS: 947692-16-2

Cefpodoxime proxetil impurity H is an impurity of cefpodoxime proxetil, which is a prodrug that has been shown to be metabolized by esterases to the active form cefpodoxime. Cefpodoxime proxetil impurity H was found in the elution fraction when using liquid chromatography with reversed-phase as the separation method. It is thought that this impurity may arise from the use of methanol in the process of preparing cefpodoxime proxetil, although other mechanisms have not been ruled out. The mass spectrum for cefpodoxime proxetil impurity H shows peaks at m/z 812 and 682, which correspond to the parent drug and its hydrolysis product, respectively. The fragmentation pattern observed for cefpodoxime proxetil impurity H corresponds to that seen for cephalosporins.

Formula: C₄₂H₅₄N₁₀O₁₈S₄

Purity: Min. 95%

Molecular weight: 1,115.2 g/mol

Ref: 3D-FC63699