CAS 949-99-5

p-Nitrophenylalanine

Description:

p-Nitrophenylalanine is an amino acid derivative characterized by the presence of a nitro group (-NO2) attached to the para position of the phenyl ring of phenylalanine. This compound is typically represented by the molecular formula C9H10N2O3 and has a molecular weight that reflects its structure. It is a crystalline solid that is soluble in polar solvents such as water and alcohol, but less soluble in non-polar solvents. p-Nitrophenylalanine is often used in biochemical research, particularly in studies involving enzyme kinetics and protein synthesis, as it can serve as a substrate or a probe for various biochemical reactions. The nitro group contributes to its unique reactivity and spectroscopic properties, making it useful in analytical chemistry. Additionally, it can exhibit both acidic and basic properties due to the presence of the amino and carboxyl functional groups, allowing it to participate in various chemical reactions. Safety precautions should be taken when handling this compound, as nitro compounds can be hazardous.

Formula: C₉H₁₀N₂O₄

InChI: InChI=1S/C9H10N2O4/c10-8(9(12)13)5-6-1-3-7(4-2-6)11(14)15/h1-4,8H,5,10H2,(H,12,13)/t8-/m0/s1

InChI key: InChIKey=GTVVZTAFGPQSPC-QMMMGPOBSA-N

SMILES: C([C@@H](C(O)=O)N)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• (2S)-2-Amino-3-(4-nitrophenyl)propanoic acid
• (2S)-2-Azaniumyl-3-(4-nitrophenyl)propanoate
• (S)-2-Amino-3-(4-nitrophenyl)propanoic acid
• (S)-4-Nitrophenylalanine
• (S)-4-Nitrophenylalanine hydrate
• 2-Amino-3-(4-nitrophenyl)propanoic acid
• 3-(4-Nitrophenyl)-<span class="text-smallcaps">L</span>-alanine
• 4-Nitro-3-phenyl-L-alanine
• 4-Nitro-<span class="text-smallcaps">L</span>-phenylalanine
• 4-Nitrophenylalanine
• <span class="text-smallcaps">L</span>-4-Nitrophenylalanine
• <span class="text-smallcaps">L</span>-Phenylalanine, 4-nitro-
• <span class="text-smallcaps">L</span>-p-Nitrophenylalanine
• Alanine, 3-(p-nitrophenyl)-, <span class="text-smallcaps">L</span>-
• H-Phe(4-NO2)-OH
• H-Phe(4-NO_2)-OH
• H-Phe(NO2)-OH . H2O
• H-p-Nitro-Phe-OH
• L-4-Nitrophe
• NSC 152925
• p-Nitro-<span class="text-smallcaps">L</span>-phenylalanine
• p-Nitrophenylalanine
• L-Phenylalanine, 4-nitro-
• 3-(4-Nitrophenyl)-L-alanine
• 4-Nitro-L-phenylalanine
• Alanine, 3-(p-nitrophenyl)-, L-

4-Nitro-L-phenylalanine

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 210.19

Ref: 3B-N0682

H-p-Nitro-Phe-OH

CAS: 949-99-5

Intermediate in the synthesis of (S)-6-nitroindoline-2-carboxylic acid.

Formula: C₉H₁₀N₂O₄

Purity: > 99%

Color and Shape: Light Yellow

Molecular weight: 210.19

Ref: 01-4000199

4-Nitro-L-phenylalanine

CAS: 949-99-5

4-Nitro-L-phenylalanine

Formula: C₉H₁₀N₂O₄

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 210.1867

Ref: 54-OR0679

4-Nitro-L-phenylalanine hydrate

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Molecular weight: 210.19

Ref: 7W-GE3304

Melphalan Impurity 1

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Color and Shape: Off-White Solid

Molecular weight: 210.19

Ref: 4Z-M-859

4-Nitro-L-phenylalanine

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 210.1867

Ref: IN-DA00IIN4

4-Nitro-L-phenylalanine

CAS: 949-99-5

M03190 - 4-Nitro-L-phenylalanine

Formula: C₉H₁₀N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 210.189

Ref: 10-M03190

H-Phe(4-NO2)-OH

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Purity: 97%

Molecular weight: 210.19

Ref: IN-DG11233

4-Nitro-L-phenylalanine

CAS: 949-99-5

4-Nitro-L-phenylalanine is a nitroprotease inhibitor that binds to the active site of the enzyme, preventing access of substrate. It is used as an analytical reagent for determination of nitrite, and has been shown to have antiviral and anti-inflammatory activities. 4-Nitro-L-phenylalanine has also been shown to inhibit the growth of human leukemia cells and enhance their sensitivity to chemotherapy drugs. This drug has been found to cause a decrease in dopamine levels in rats and may be useful in the treatment of Parkinson's disease.

Formula: C₉H₁₀N₂O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 210.19 g/mol

Ref: 3D-FN46969

4-Nitro-L-phenylalanine

Controlled Product

CAS: 949-99-5

Applications 4-Nitro-L-phenylalanine is used in the studies on the rational manipulation of protein structures for the expansion of the genetic code with non natural amino acids into protein via in vitro translation.
References Wang, L., et al.: Angew. Chem., Int. Ed., 44, 34 (2005); Hohsaka, T., et al.: Nucleic Acids Symp. Ser., 39, 165 (1998)

Formula: C₉H₁₀N₂O₄

Color and Shape: Neat

Molecular weight: 210.19

Ref: TR-N496630

4-Nitro-L-Phenylalanine

CAS: 949-99-5

Formula: C₉H₁₀N₂O₄

Molecular weight: 210.19

Ref: ST-EA-CP-M9016