CymitQuimica logo

CAS 95153-31-4

:

Perindoprilat

Description:
Perindoprilat is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor perindopril, primarily used in the treatment of hypertension and heart failure. It is characterized by its ability to inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. Perindoprilat is a white to off-white crystalline powder that is soluble in water and exhibits a pKa indicative of its acidic nature. Its molecular structure includes a carboxyl group, which contributes to its pharmacological activity. The compound has a relatively long half-life, allowing for once-daily dosing in clinical settings. Additionally, perindoprilat is known for its favorable side effect profile, making it a commonly prescribed medication. It is important to monitor renal function and potassium levels in patients taking this medication, as it can affect renal hemodynamics and electrolyte balance. Overall, perindoprilat plays a significant role in cardiovascular therapy, demonstrating efficacy in reducing morbidity and mortality associated with heart disease.
Formula:C17H28N2O5
InChI:InChI=1S/C17H28N2O5/c1-3-6-12(16(21)22)18-10(2)15(20)19-13-8-5-4-7-11(13)9-14(19)17(23)24/h10-14,18H,3-9H2,1-2H3,(H,21,22)(H,23,24)/t10-,11-,12-,13-,14-/m0/s1
InChI key:InChIKey=ODAIHABQVKJNIY-PEDHHIEDSA-N
SMILES:C([C@@H](N[C@@H](CCC)C(O)=O)C)(=O)N1[C@@]2([C@](C[C@H]1C(O)=O)(CCCC2)[H])[H]
Synonyms:
  • (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
  • (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-Carboxybutyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid (non-preferred name)
  • (2S-(1(R*(R*)),2a,3ab,7ab))-Octahydro-1-(2-((1-carboxybutyl)amino)-1-oxopropyl)-1H-indole-2-carboxylic Acid
  • 1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-carboxybutyl]amino]-1-oxopropyl]octahydro-, (2S,3aS,7aS)-
  • 1H-Indole-2-carboxylic acid, 1-[2-[(1-carboxybutyl)amino]-1-oxopropyl]octahydro-, [2S-[1[R*(R*)],2α,3aβ,7aβ]]-
  • 95153-31-4
  • S 9780
  • Perindoprilat
  • Perindopril EP IMpurity-B(USP RC B)
  • Perindoprilat (Mixture of Diastereomers)
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.