CAS 952652-79-8

Valsartan Related Compound B (N-butyryl-N-{[2'-(1H-tetrazole-5-yl)-biphenyl-4-yl]methyl}-L-valine)

CAS: 952652-79-8

Aromatic or modified aromatic drugs with nitrogen heter

Formula: C₂₃H₂₇N₅O₃

Color and Shape: White Powder

Molecular weight: 421.21139

Ref: 45-1708784

Valsartan n-Propyl

CAS: 952652-79-8

Formula: C₂₃H₂₇N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 421.4922

Ref: IN-DA00IIWL

Valsartan EP Impurity C (Valsartan USP Related Compound B)

CAS: 952652-79-8

Formula: C₂₃H₂₇N₅O₃

Color and Shape: Off-White Solid

Molecular weight: 421.50

Ref: 4Z-V-026

(2S)-2-[Butanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]-3-methylbutanoic Acid

CAS: 952652-79-8

Color and Shape: Neat

Ref: 86-MM0487.04

Valsartan Impurity 46

CAS: 952652-79-8

Formula: C₂₅H₃₁N₅O₃

Color and Shape: Off-White Solid

Molecular weight: 449.56

Ref: 4Z-V-0268

Valsartan n-Propyl Impurity

Controlled Product

CAS: 952652-79-8

Impurity Valsartan Related Compound B
Applications Valsartan n-Propyl is an impurity in the synthesis of Valsartan (V095750). Valsartan USP Related Compound B.
References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 31, 329 (2003), Carlucci, G., et al.: Anal. Lett., 33, 2491 (2000), Cagigal, E., et al.: Talanta, 54, 1121 (2001),

Formula: C₂₃H₂₇N₅O₃

Color and Shape: White

Molecular weight: 421.49

Ref: TR-V095770

Valsartan EP Impurity C

CAS: 952652-79-8

Formula: C₂₃H₂₇N₅O₃

Molecular weight: 421.49

Ref: ST-EA-CP-V3003

N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine

CAS: 952652-79-8

N-(1-Oxobutyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine (GW1929) is a potent vasodilator that is used for the treatment of hypertension. It is synthesized by condensation of sodium hydroxide with 2-(4′-chlorophenyl)piperazine followed by methyl esterification and chloride acylation. The synthesis of GW1929 has been accomplished in two steps: carbonate cyclization and valsartan hydrolysis. In the first step, the carboxylic acid group of GW1929 was converted to its corresponding chloride compound which was then reacted with methyl bromide to yield the desired product. The second step involved hydrolysis of GW1929 with potassium carbonate, after which it was oxidized with azide to form an ester. Sodium

Formula: C₂₃H₂₇N₅O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 421.49 g/mol

Ref: 3D-IO28664