CAS 953769-46-5

Formula: C20H22N4O3S

InChI: InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1

InChI key: ADZBMFGQQWPHMJ-RHSMWYFYSA-N

SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)Amino)Benzo[D]Thiazol-6-Yl)Oxy)-N-Methylpicolinamide

CAS: 953769-46-5

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)Amino)Benzo[D]Thiazol-6-Yl)Oxy)-N-Methylpicolinamide

Formula: C₂₀H₂₂N₄O₃S

Purity: 98%

Molecular weight: 398.48

Ref: 54-OR1024387

Sotuletinib

CAS: 953769-46-5

Sotuletinib

Formula: C₂₀H₂₂N₄O₃S

Purity: 99.5%

Molecular weight: 398.48

Ref: 54-BUP15067

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide

CAS: 953769-46-5

4-((2-(((1R,2R)-2-Hydroxycyclohexyl)amino)benzo[d]thiazol-6-yl)oxy)-N-methylpicolinamide

Formula: C₂₀H₂₂N₄O₃S

Purity: 98%

Molecular weight: 398.48

Ref: IN-DG303841

BLZ-945

CAS: 953769-46-5

Formula: C₂₀H₂₂N₄O₃S

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 398.5

Ref: 7W-GL2252

Sotuletinib

CAS: 953769-46-5

Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.

Formula: C₂₀H₂₂N₄O₃S

Purity: 97.43% - 99.82%

Color and Shape: Yellow Solid

Molecular weight: 398.48

Ref: TM-T6119

4-((2-(((1R,2R)-2-HYDROXYCYCLOHEXYL)AMINO)BENZO[D]THIAZOL-6-YL)OXY)-N-METHYLPICOLINAMIDE

CAS: 953769-46-5

Formula: C₂₀H₂₂N₄O₃S

Purity: 98%

Molecular weight: 398.48

Ref: 10-F501110

BLZ 945

CAS: 953769-46-5

BLZ 945 is a novel small molecule that inhibits the activation of microglia, which are immune cells in the brain. It has been shown to inhibit tumor growth and radiation-induced tissue damage in cancer research. BLZ 945 also reduces the severity of autoimmune diseases by inhibiting the production of pro-inflammatory cytokines such as csf-1r and toll-like receptor 4. In addition, it has anti-inflammatory properties due to its inhibition of macrophage migration and adhesion. The drug has been shown to reduce the size of solid tumours in mice by reducing tumor angiogenesis and inhibiting cell proliferation.

Formula: C₂₀H₂₂N₄O₃S

Purity: Min. 95%

Molecular weight: 398.48 g/mol

Ref: 3D-BB178452

4-[[2-[[(1R,2R)-2-Hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide

CAS: 953769-46-5

Formula: C₂₀H₂₂N₄O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.4787

Ref: IN-DA00368U