CAS 955094-26-5

MaleiMide-NH-PEG2-NHS Ester

Description:

Maleimide-NH-PEG2-NHS ester is a chemical compound that features a maleimide functional group, which is known for its ability to form stable thioether bonds with thiol-containing molecules, making it useful in bioconjugation applications. The presence of a polyethylene glycol (PEG) moiety enhances the solubility and biocompatibility of the compound, which is particularly advantageous in pharmaceutical and biomedical contexts. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling reactions with amine-containing compounds, facilitating the formation of stable amide bonds. This compound is often utilized in the development of targeted drug delivery systems, protein labeling, and the synthesis of bioconjugates for diagnostic and therapeutic purposes. Its characteristics include a relatively low molecular weight, high reactivity towards nucleophiles, and the ability to form covalent bonds under mild conditions, making it a versatile tool in chemical biology and materials science. Proper handling and storage conditions are essential to maintain its stability and reactivity.

Synonyms:

• α-Maleimidopropionyl-ω-succinimidyl-2(ethylene glycol)
• Mal-PEG2-NHS
• alpha-MaleiMidopropionyl-oMega-succiniMidyl-2(ethylene glycol)
• 3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
• MaleiMide-PEG2-succiniMidyl ester

Maleimide-PEG2-NHS Ester

CAS: 955094-26-5

Formula: C₁₈H₂₃N₃O₉

Purity: >98.0%(GC)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 425.39

Ref: 3B-M3079

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoate

CAS: 955094-26-5

Formula: C₁₈H₂₃N₃O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 425.3899

Ref: IN-DA00IJ65

Mal-amido-PEG2-NHS ester

CAS: 955094-26-5

Noncleavable ADC linker with maleimide group and NHS ester for labeling proteins and amine-modified molecules.

Formula: C₁₈H₂₃N₃O₉

Color and Shape: Solid

Molecular weight: 425.39

Ref: TM-T15951

Maleimide-PEG2-NHS Ester (2mg×5)

CAS: 955094-26-5

Formula: C₁₈H₂₃N₃O₉

Color and Shape: White to Light yellow powder to crystaline

Molecular weight: 425.39

Ref: 3B-M3339

Mal-amido-PEG2-NHS

CAS: 955094-26-5

Mal-amido-PEG2-NHS

Purity: 95%

Molecular weight: 425.39g/mol

Ref: 54-BIPG1477

Maleimide-PEG2-succinimidyl ester

CAS: 955094-26-5

Maleimide-PEG2-succinimidyl ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), these types of compounds are more versatile as they have two different anchor points. Maleimide-PEG2-succinimidyl ester is used as a linker to both thiols and amines, and as a spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules, and nanoparticles.

Formula: C₁₈H₂₃N₃O₉

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 425.39 g/mol

Ref: 3D-FM73025

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoate

CAS: 955094-26-5

Purity: 95%

Color and Shape: Solid

Molecular weight: 425.3940125

Ref: 10-F863963

MAL-dPEG®2-NHS Ester

CAS: 955094-26-5

MAL-dPEG®2-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), these types of compounds are more versatile as they have two different anchor points. MAL-dPEG®2-NHS Ester is used as a non-cleavable linker and as a spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules, and nanoparticles.

Purity: Min. 95%

Molecular weight: 425.39 g/mol

Ref: 3D-DPG-5765