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CAS 955094-26-5

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MaleiMide-NH-PEG2-NHS Ester

Description:
Maleimide-NH-PEG2-NHS ester is a chemical compound that features a maleimide functional group, which is known for its ability to form stable thioether bonds with thiol-containing molecules, making it useful in bioconjugation applications. The presence of a polyethylene glycol (PEG) moiety enhances the solubility and biocompatibility of the compound, which is particularly advantageous in pharmaceutical and biomedical contexts. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling reactions with amine-containing compounds, facilitating the formation of stable amide bonds. This compound is often utilized in the development of targeted drug delivery systems, protein labeling, and the synthesis of bioconjugates for diagnostic and therapeutic purposes. Its characteristics include a relatively low molecular weight, high reactivity towards nucleophiles, and the ability to form covalent bonds under mild conditions, making it a versatile tool in chemical biology and materials science. Proper handling and storage conditions are essential to maintain its stability and reactivity.
Formula:C18H23N3O9
InChI:InChI=1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)
InChI key:TZPDZOJURBVWHS-UHFFFAOYSA-N
SMILES:C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)CCN2C(=O)C=CC2=O
Synonyms:
  • α-Maleimidopropionyl-ω-succinimidyl-2(ethylene glycol)
  • Mal-PEG2-NHS
  • alpha-MaleiMidopropionyl-oMega-succiniMidyl-2(ethylene glycol)
  • 3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
  • MaleiMide-PEG2-succiniMidyl ester
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