CAS 955328-22-0

4-amino-8-chloro-quinoline-3-carboxylic acid

Description:

4-Amino-8-chloro-quinoline-3-carboxylic acid is a chemical compound characterized by its quinoline structure, which consists of a bicyclic aromatic system containing a nitrogen atom. This compound features an amino group (-NH2) and a carboxylic acid group (-COOH) that contribute to its polar nature, enhancing its solubility in polar solvents. The presence of a chlorine atom at the 8-position of the quinoline ring introduces additional reactivity and influences its biological activity. This compound is often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its structural similarity to other bioactive molecules. Its unique functional groups may also allow for various chemical modifications, making it a versatile intermediate in organic synthesis. Additionally, the compound's properties, such as melting point, boiling point, and spectral characteristics, can be determined through experimental methods, providing insights into its behavior in different chemical environments. Overall, 4-amino-8-chloro-quinoline-3-carboxylic acid is of interest for its potential therapeutic applications and as a building block in chemical synthesis.

Formula: C₁₀H₇ClN₂O₂

InChI: InChI=1/C10H7ClN2O2/c11-7-3-1-2-5-8(12)6(10(14)15)4-13-9(5)7/h1-4H,(H2,12,13)(H,14,15)

InChI key: DMQKTDVVSMSBCL-UHFFFAOYSA-N

SMILES: c1cc2c(c(cnc2c(c1)Cl)C(=O)O)N

Synonyms:

• 3-Quinolinecarboxylic acid, 4-amino-8-chloro-
• 4-Amino-8-chloroquinoline-3-carboxylic acid

4-Amino-8-chloroquinoline-3-carboxylic Acid

Controlled Product

CAS: 955328-22-0

Formula: C₁₀H₇ClN₂O₂

Color and Shape: Neat

Molecular weight: 222.628

Ref: TR-A621530

FTO-IN-12

CAS: 955328-22-0

FTO-IN-12 (Compound 2), an inhibitor of fat mass and obesity-related protein (FTO), exhibits Kd and IC₅₀ values of 185 nM and 1.46 μM, respectively. This compound is utilized in researching neurodegenerative diseases.

Formula: C₁₀H₇ClN₂O₂

Color and Shape: Solid

Molecular weight: 222.628

Ref: TM-T88144