CAS: 955365-80-7 - 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

Formula: C₂₇H₃₂N₈O₂

InChI: InChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-17H2,2-4H3,(H,28,29,31)

InChI key: InChIKey=BKWJAKQVGHWELA-UHFFFAOYSA-N

SMILES: O=C1C2=CN=C(N=C2N(C=3N=C(C=CC3)C(O)(C)C)N1CC=C)NC4=CC=C(C=C4)N5CCN(C)CC5

Synonyms:

• 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one
• 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one
• 2-Allyl-1,8-Dimethoxy-9,10-Anthraquinone
• 2-Allyl-1,8-Dimethoxyanthracene-9,10-Dione
• 2-allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one
• 3H-Pyrazolo[3,4-d]pyrimidin-3-one, 1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-
• 9,10-Anthracenedione,1,8-dimethoxy-2-(2-propenyl)
• Adavosertib
• Azd 1775
• Azd1775
• Mk-1775
• Wee 1-1

2-Allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one

CAS: 955365-80-7

• Formula: C₂₇H₃₂N₈O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 500.5954

Adavosertib

CAS: 955365-80-7

Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). …

• Formula: C₂₇H₃₂N₈O₂
• Purity: 100%
• Color and Shape: Solid
• Molecular weight: 500.6

Adavosertib (MK-1775)

CAS: 955365-80-7

• Formula: C₂₇H₃₂N₈O₂
• Molecular weight: 500.61

MK 1775

CAS: 955365-80-7

Applications MK 1775 is used in biological studies for the abrogation of G2/M checkpoint through …

• Formula: C₂₇H₃₂N₈O₂
• Color and Shape: Pale Yellow to Light Yellow Solid
• Molecular weight: 500.6

MK 1775

CAS: 955365-80-7

Wee1 inhibitor with an IC50 of 5.2 nM

• Formula: C₂₇H₃₂N₈O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 500.6 g/mol

MK 1775-d3

CAS: 955365-80-7

• Formula: C₂₇H₂₉D₃N₈O₂
• Molecular weight: 503.61