CAS: 956104-40-8 - ARN 509

Formula: C₂₁H₁₅F₄N₅O₂S

InChI: InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)

InChI key: InChIKey=HJBWBFZLDZWPHF-UHFFFAOYSA-N

SMILES: N#CC1=NC=C(C=C1C(F)(F)F)N2C(=O)C3(N(C4=CC=C(C(=O)NC)C(F)=C4)C2=S)CCC3

Synonyms:

• 4-[7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide
• 4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
• Apalutamide
• Ar 509
• Benzamide, 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-
• Erleada

ARN-509

CAS: 956104-40-8

• Formula: C₂₁H₁₅F₄N₅O₂S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 477.4347

Apalutamide

CAS: 956104-40-8

• Formula: C₂₁H₁₅F₄N₅O₂S
• Color and Shape: Off-White Solid
• Molecular weight: 477.44

Apalutamide-13C-d3

CAS: 956104-40-8

• Formula: C₂₀₁₃CH₁₂D₃F₄N₅O₂S
• Color and Shape: White To Off-White Solid
• Molecular weight: 481.45

Apalutamide

CAS: 956104-40-8

• Formula: C₂₁H₁₅F₄N₅O₂S
• Color and Shape: Neat
• Molecular weight: 477.4347

Apalutamide

CAS: 956104-40-8

Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.

• Formula: C₂₁H₁₅F₄N₅O₂S
• Purity: 99.03% - 99.97%
• Color and Shape: Solid
• Molecular weight: 477.43

Apalutamide

CAS: 956104-40-8

Applications Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer. References Li, …

• Formula: C₂₁H₁₅F₄N₅O₂S
• Color and Shape: White To Off-White
• Molecular weight: 477.4347

ARN 509

CAS: 956104-40-8

A potent antagonist of androgen receptor with IC50 value of 16 nM. Binds androgen receptors, …

• Formula: C₂₁H₁₅F₄N₅O₂S
• Purity: Min. 95%
• Color and Shape: White Off-White Powder
• Molecular weight: 477.44 g/mol

Apalutamide-d7

CAS: 956104-40-8

• Formula: C₂₁H₈D₇F₄N₅O₂S
• Color and Shape: Neat
• Molecular weight: 484.48