CAS 95635-55-5: Ranolazine
Description:Ranolazine is an antianginal medication primarily used to treat chronic stable angina pectoris. It functions by inhibiting the late sodium current in cardiac myocytes, which helps to reduce intracellular sodium and calcium overload, ultimately improving myocardial oxygen efficiency. The chemical formula of ranolazine is C24H33N3O4S, and it has a molecular weight of approximately 427.6 g/mol. This compound is characterized by its unique structure, which includes a piperazine ring and a thiazole moiety. Ranolazine is typically administered orally and is known for its relatively low side effect profile compared to traditional antianginal therapies. It does not significantly affect heart rate or blood pressure, making it suitable for patients who may not tolerate other medications. Additionally, ranolazine has been shown to have metabolic effects, potentially improving glucose metabolism in diabetic patients. Its pharmacokinetics involve extensive hepatic metabolism, primarily via the cytochrome P450 system, and it has a moderate half-life, necessitating careful consideration of dosing regimens.
Formula:C24H33N3O4
InChI:InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
InChI key:InChIKey=XKLMZUWKNUAPSZ-UHFFFAOYSA-N
SMILES:O=C(NC=1C(=CC=CC1C)C)CN2CCN(CC2)CC(O)COC=3C=CC=CC3OC
- Synonyms:
- (±)-N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propry]-1-piperazine acetamide
- 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-
- 1-[3-(2-Methoxyphenoxy)-2-Hydroxypropyl]-4-[(2,6-Dimethylphenyl)Aminocarbonylmethy]Piperazine
- 4-(Pyrimidin-2-ylmethyl)-7-(4-(trifluoromethyl)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one
- Cvt 303
- N-(2,6-Dimethylphenyl)-2-[4-[2-Hydroxy-3-(2-Methoxyphenoxy)Propyl]Piperazin-1-Yl]Acetamide
- N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide
- Ranexa
- Renexa
- Rs 43285-003
- See more synonyms
- Ranolazine
- (±)-Ranolazine
