CAS 95635-55-5
:Ranolazine
Description:
Ranolazine is an antianginal medication primarily used to treat chronic stable angina pectoris. It functions by inhibiting the late sodium current in cardiac myocytes, which helps to reduce intracellular sodium and calcium overload, ultimately improving myocardial oxygen efficiency. The chemical formula of ranolazine is C24H33N3O4S, and it has a molecular weight of approximately 427.6 g/mol. This compound is characterized by its unique structure, which includes a piperazine ring and a thiazole moiety. Ranolazine is typically administered orally and is known for its relatively low side effect profile compared to traditional antianginal therapies. It does not significantly affect heart rate or blood pressure, making it suitable for patients who may not tolerate other medications. Additionally, ranolazine has been shown to have metabolic effects, potentially improving glucose metabolism in diabetic patients. Its pharmacokinetics involve extensive hepatic metabolism, primarily via the cytochrome P450 system, and it has a moderate half-life, necessitating careful consideration of dosing regimens.
Formula:C24H33N3O4
InChI:InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
InChI key:InChIKey=XKLMZUWKNUAPSZ-UHFFFAOYSA-N
SMILES:O(CC(CN1CCN(CC(NC2=C(C)C=CC=C2C)=O)CC1)O)C3=C(OC)C=CC=C3
Synonyms:- (±)-N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propry]-1-piperazine acetamide
- 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-
- 1-[3-(2-Methoxyphenoxy)-2-Hydroxypropyl]-4-[(2,6-Dimethylphenyl)Aminocarbonylmethy]Piperazine
- 4-(Pyrimidin-2-ylmethyl)-7-(4-(trifluoromethyl)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one
- Cvt 303
- N-(2,6-Dimethylphenyl)-2-[4-[2-Hydroxy-3-(2-Methoxyphenoxy)Propyl]Piperazin-1-Yl]Acetamide
- N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide
- Ranexa
- Renexa
- Rs 43285-003
- Ranolazine
- See more synonyms
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Ranolazine
CAS:Formula:C24H33N3O4Purity:>95.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:427.55Ranolazine
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:C24H33N3O4Color and Shape:White Off-White Crystalline PowderMolecular weight:427.24711Ranolazine-d5
CAS:Formula:C24H28D5N3O4Color and Shape:White To Off-White SolidMolecular weight:432.58N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide
CAS:Formula:C24H33N3O4Purity:98%Color and Shape:SolidMolecular weight:427.5365Ref: IN-DA00H8QM
1mg24.00€100mg24.00€1g25.00€250mg28.00€5g56.00€10g69.00€15g99.00€25g115.00€50g213.00€75g267.00€100g332.00€Ranolazine
CAS:Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.Formula:C24H33N3O4Purity:98.13%Color and Shape:White SolidMolecular weight:427.5365Ranolazine
CAS:N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamideFormula:C24H33N3O4Purity:98%Molecular weight:427.54Ranolazine - Bio-X ™
CAS:Ranolazine is a group P2 drug that reverses the pathogenic mechanism of myocardial infarction. It is used to treat chronic angina. It decreases myocardial wall tension and improves coronary blood flow. It inhibits the ryanodine receptor, which is responsible for regulating the release of intracellular calcium in cardiac and skeletal muscle cells. Furthermore, it is also effective at preventing atrial fibrillation and has been studied as monotherapy as well as in combination with other medications used to treat irregular heartbeat.
Formula:C24H33N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:427.54 g/molN-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide
CAS:Formula:C24H33N3O4Purity:95.0%Color and Shape:SolidMolecular weight:427.545
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