CAS 957-56-2

Fluindione

Description:

Fluindione, with the CAS number 957-56-2, is an anticoagulant medication that belongs to the class of vitamin K antagonists. It is primarily used in the prevention and treatment of thromboembolic disorders, such as deep vein thrombosis and pulmonary embolism. The chemical structure of fluindione features a 1,3-indandione core, which is essential for its pharmacological activity. As a synthetic compound, it exhibits a high degree of lipophilicity, allowing for effective absorption and distribution within the body. Fluindione functions by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver, thereby reducing the blood's ability to clot. Its pharmacokinetics include a relatively long half-life, which necessitates careful monitoring of coagulation parameters to avoid complications such as bleeding. Additionally, fluindione may interact with various medications and dietary factors, making patient management crucial during therapy. Overall, fluindione is a significant agent in anticoagulation therapy, although its use has declined in favor of newer alternatives with more predictable dosing and fewer interactions.

Formula: C₁₅H₉FO₂

InChI: InChI=1/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H

InChI key: InChIKey=NASXCEITKQITLD-UHFFFAOYSA-N

SMILES: O=C1C(C(=O)C=2C1=CC=CC2)C3=CC=C(F)C=C3

Synonyms:

• 1,3-Indandione, 2-(p-fluorophenyl)-
• 1H-Indene-1,3(2H)-dione, 2-(4-fluorophenyl)-
• 2-(4-fluorophenyl)-1H-indene-1,3(2H)-dione
• 2-(p-Fluorophenyl)-1,3-indandione
• Brn 2052411
• Fluindiona
• Fluindiona [INN-Spanish]
• Fluindione [INN]
• Fluindionum
• Fluindionum [INN-Latin]
• Lm 123
• Previscan
• Unii-Eq35Yms20Q
• Fluindione
• fluorindione
• 2-(4-fluorophenyl)indene-1,3-dione

Fluindione

CAS: 957-56-2

Purity: 95%

Ref: IN-DA005XFO

Fluindione

CAS: 957-56-2

Fluindione

Formula: C₁₅H₉FO₂

Purity: ≥95%

Molecular weight: 240.23

Ref: 54-PC1034055

Fluindione

CAS: 957-56-2

Formula: C₁₅H₉FO₂

Color and Shape: White To Off-White Solid

Molecular weight: 240.24

Ref: 4Z-F-221

Fluindione

Controlled Product

CAS: 957-56-2

Formula: C₁₅H₉FO₂

Color and Shape: Neat

Molecular weight: 240.23

Ref: 86-MM3728.00

Fluindione

Controlled Product

CAS: 957-56-2

Applications A vitamin K antagonist with anticoagulant applications
References Streiff, M., et al.: Am. J. Hematol., 81, 684 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Tavassoli, N., et al.: Eur. J. Clin. Pharmacol., 63, 221 (2007), Bodin, L., et al.: J. Thromb. Haemost., 6, 1436 (2008),

Formula: C₁₅H₉FO₂

Color and Shape: Neat

Molecular weight: 240.23

Ref: TR-F436000

Fluindione

CAS: 957-56-2

Ref: BE-RMCF111000

Fluindione-[13C6]

CAS: 957-56-2

Ref: BE-MC-7793

Fluindione

CAS: 957-56-2

Fluindione is a hematologic drug.

Formula: C₁₅H₉FO₂

Color and Shape: Solid

Molecular weight: 240.23

Ref: TM-T20798

Fluindione

CAS: 957-56-2

Formula: C₁₅H₉FO₂

Molecular weight: 240.24

Ref: ST-EA-CP-F136000