CAS 95715-87-0

(R)-Garner aldehyde

Description:

(R)-Garner aldehyde, with the CAS number 95715-87-0, is a chiral organic compound characterized by its unique structure and properties. It is primarily recognized for its role in organic synthesis, particularly in the preparation of various pharmaceuticals and biologically active molecules. The compound features a specific stereochemistry, which is crucial for its reactivity and interaction with biological systems. As an aldehyde, it contains a carbonyl group (C=O) at the terminal position of a carbon chain, contributing to its reactivity in nucleophilic addition reactions. (R)-Garner aldehyde is often utilized in asymmetric synthesis due to its ability to influence the stereochemical outcome of reactions. Its physical properties, such as boiling point and solubility, are typical of aldehydes, making it a versatile intermediate in synthetic organic chemistry. Additionally, the compound's chirality allows for the exploration of enantioselective reactions, which are essential in the development of enantiomerically pure compounds in medicinal chemistry.

Formula: C₁₁H₁₉NO₄

InChI: InChI=1S/C11H19NO4/c1-10(2,3)16-9(14)12-8(6-13)7-15-11(12,4)5/h6,8H,7H2,1-5H3/t8-/m0/s1

InChI key: InChIKey=PNJXYVJNOCLJLJ-QMMMGPOBSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@@H](C=O)COC1(C)C

Synonyms:

• (4R)-4-Formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylic acid tert-butyl ester
• (R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde
• (R)-(+)-3-tert-Butoxycarbonyl-2,2-dimethyloxazolidine-4-carboxaldehyde
• (R)-2,2-Dimethyl-3-tert-butoxycarbonyl-1,3-oxazolidine-4-carboxaldehyde
• (R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine
• (R)-4-Formyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester
• (R)-Garner aldehyde
• (R)-Garner's aldehyde
• (R)-tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate
• (S)-3-N-Boc-aminopyrrolidine
• 1,1-Dimethylethyl (R)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate
• 3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R)-
• 3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (R)-
• ent-Garner's aldehyde
• tert-Butyl (4R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate
• tert-Butyl (R)-(+)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate

(4R)-2,2-Dimethyl-1,3-oxazolidine-4-carboxaldehyde, N-BOC protected

CAS: 95715-87-0

(4R)-2,2-Dimethyl-1,3-oxazolidine-4-carboxaldehyde, N-BOC protected

Formula: C₁₁H₁₉NO₄

Purity: 97%

Color and Shape: Liquid-Viscous

Molecular weight: 229.27286

Ref: 54-OR313059

(R)-tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

CAS: 95715-87-0

Formula: C₁₁H₁₉NO₄

Purity: 97%

Color and Shape: Liquid

Molecular weight: 229.2729

Ref: IN-DA0032FE

(R)-tert-Butyl 4-Formyl-2,2-dimethyloxazolidine-3-carboxylate

CAS: 95715-87-0

Formula: C₁₁H₁₉NO₄

Purity: >95.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 229.28

Ref: 3B-B5351

(R)-4-Formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

CAS: 95715-87-0

Formula: C₁₁H₁₉NO₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 229.276

Ref: 10-F040765

(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine

Controlled Product

CAS: 95715-87-0

Formula: C₁₁H₁₉NO₄

Color and Shape: Neat

Molecular weight: 229.27

Ref: TR-B690120

(R)-tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

CAS: 95715-87-0

(R)-tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

Formula: C₁₁H₁₉NO₄

Purity: 97%

Molecular weight: 229.27

Ref: IN-DG35511

(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine

CAS: 95715-87-0

The present invention relates to a method for the synthesis of (4R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine. The method is based on a new and efficient allylation reaction using an allyl alcohol as the electrophile. This method allows for the production of this compound in high yield and with excellent stereoselectivity. It also provides a convenient route to prepare (4R)-3-tert-butoxycarbonyl oxindole in good yield and high stereoselectivity. This product has been shown to have antiinflammatory properties that are due to its ability to inhibit prostaglandin synthesis.

Formula: C₁₁H₁₉NO₄

Purity: Min. 98%

Color and Shape: Clear Liquid

Molecular weight: 229.27 g/mol

Ref: 3D-FB19415