CAS 957229-52-6

Formula: C27H30F6N2O2

InChI: InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21-,24-,25+/m0/s1

InChI key: JWJOTENAMICLJG-LKOHVCGWSA-N

SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@H]5[C@@]3(C=CC(=O)N5)C

5-β-Dutasteride

CAS: 957229-52-6

Formula: C₂₇H₃₀F₆N₂O₂

Color and Shape: Off-White Solid

Molecular weight: 528.54

Ref: 4Z-D-355

5Beta-Dutasteride

Controlled Product

CAS: 957229-52-6

Applications 5β-Dutasteride is the β-isomer impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2.
References Satyanarayana, K. et al.: Pharmazie, 62, 743 (2007);

Formula: C₂₇H₃₀F₆N₂O₂

Color and Shape: Neat

Molecular weight: 528.53

Ref: TR-D735005

5β-​Dutasteride

CAS: 957229-52-6

Formula: C₂₇H₃₀F₆N₂O₂

Molecular weight: 528.5

Ref: BE-RMCD250043

5β-Dutasteride

CAS: 957229-52-6

Formula: C₂₇H₃₀F₆N₂O₂

Molecular weight: 528.5

Ref: ST-EA-CP-D30014

5β-​Dutasteride

CAS: 957229-52-6

5β-Dutasteride is the S configuration of Dutasteride. It is a potent inhibitor of both 5 alpha-reductase isozymes.

Formula: C₂₇H₃₀F₆N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 528.53

Ref: TM-T10179

5β-​Dutasteride

CAS: 957229-52-6

5β-Dutasteride is a research tool that belongs to the class of ligands. Its binding site is the Androgen Receptor (AR) and it is an antagonist. The binding of 5β-dutasteride to AR prevents the interaction with cofactors, such as 3-alpha hydroxysteroid dehydrogenase and 17,20 lyase, which are required for the synthesis of testosterone. This compound was also shown to inhibit ion channels by blocking potassium currents. The high purity and quality of this product makes it suitable for use in cell biology, pharmacology, and protein interactions.

Formula: C₂₇H₃₀F₆N₂O₂

Purity: Min. 95%

Molecular weight: 528.5 g/mol

Ref: 3D-HNB22952